In vivo tracking of bioorthogonally labeled T-cells for predicting therapeutic efficacy of adoptive T-cell therapy

Non-invasive tracking of T-cells may help to predict the patient responsiveness and therapeutic outcome. Herein, we developed bioorthogonal T-cell labeling and tracking strategy using bioorthogonal click chemistry. First, ovalbumin (OVA) antigen-specific cytotoxic T-cells (CTLs) were incubated with...

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Veröffentlicht in:	Journal of controlled release 2021-01, Vol.329, p.223-236
Hauptverfasser:	Kim, Woojun, Yoon, Hong Yeol, Lim, Seungho, Stayton, Patrick S., Kim, In-San, Kim, Kwangmeyung, Kwon, Ick Chan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive T-cell therapy Bioorthogonal click chemistry in vivo imaging T-cell tracking
Online-Zugang:	Volltext
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