Klotho gene G395A and C1818T polymorphisms in acromegaly: Association with clinical presentation and comorbidities

Background Klotho is a new identified anti‐ageing gene with tumour suppressor activities. Current data suggest that there is a tight relationship between Klotho protein and growth hormone (GH)/insulin‐like growth factor‐1 (IGF‐1) axis. Purpose This study aimed to investigate the possible association...

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Veröffentlicht in:	Clinical endocrinology (Oxford) 2021-04, Vol.94 (4), p.598-605
Hauptverfasser:	Helvaci, Nafiye, Kabacam, Serkan, Dagdelen, Selcuk, Lay, Incilay, Karabulut, Erdem, Mut, Melike, Alikasifoglu, Mehmet, Erbas, Tomris
Format:	Artikel
Sprache:	eng
Schlagworte:	Acromegaly Adenoma Aging cancer Gene polymorphism Growth hormones Insulin Insulin-like growth factors insulin‐like growth factor‐1 Klotho Klotho protein Malignancy Polymorphism Polyps Serum levels single nucleotide polymorphism Tumor suppressor genes Tumors
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