Brain Structure Alterations in Hemifacial Spasm: A Diffusion Tensor Imaging Study
This study examined white matter integrity in patients with left-sided hemifacial spasm (HFS) using diffusion tensor imaging (DTI). Thirty-six patients with left-sided HFS (mean age 53.24 ± 8.16 years) and 36 healthy volunteers (mean age 53.92 ± 7.73 years) were recruited. Tract-based spatial statis...
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| Veröffentlicht in: | Clinical EEG and neuroscience 2022-03, Vol.53 (2), p.165-172 |
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| creator | Zhang, Jian Yu, Qingyang Gu, Peng Sun, Hongtao Yuan, Fei Zhang, Quan |
| description | This study examined white matter integrity in patients with left-sided hemifacial spasm (HFS) using diffusion tensor imaging (DTI). Thirty-six patients with left-sided HFS (mean age 53.24 ± 8.16 years) and 36 healthy volunteers (mean age 53.92 ± 7.73 years) were recruited. Tract-based spatial statistics (TBSS) analysis revealed significantly increased fractional anisotropy (FA) of bilateral superior longitudinal fasciculus in HFS patients (P < 0.05, family-wise error corrected), with trends for radial diffusivity to decrease. We inferred that the results may be associated with poor sleep quality, impairment in visuospatial construction, and activity-dependent increases in myelination in HFS patients. Furthermore, the FA value of left superior longitudinal fasciculus showed a positive correlation with HFS duration (r = 0.352, P = .041) and spasm severity (r = 0.416, P = .014). However, the alteration of medial diffusivity and axial diffusivity were not found in bilateral superior longitudinal fasciculus between groups. These findings suggest FA changes of superior longitudinal fasciculus reflected by TBSS analysis may provide valuable insights into the diagnosis of HFS. |
| doi_str_mv | 10.1177/1550059420979250 |
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Thirty-six patients with left-sided HFS (mean age 53.24 ± 8.16 years) and 36 healthy volunteers (mean age 53.92 ± 7.73 years) were recruited. Tract-based spatial statistics (TBSS) analysis revealed significantly increased fractional anisotropy (FA) of bilateral superior longitudinal fasciculus in HFS patients (P < 0.05, family-wise error corrected), with trends for radial diffusivity to decrease. We inferred that the results may be associated with poor sleep quality, impairment in visuospatial construction, and activity-dependent increases in myelination in HFS patients. Furthermore, the FA value of left superior longitudinal fasciculus showed a positive correlation with HFS duration (r = 0.352, P = .041) and spasm severity (r = 0.416, P = .014). However, the alteration of medial diffusivity and axial diffusivity were not found in bilateral superior longitudinal fasciculus between groups. These findings suggest FA changes of superior longitudinal fasciculus reflected by TBSS analysis may provide valuable insights into the diagnosis of HFS.</description><identifier>ISSN: 1550-0594</identifier><identifier>EISSN: 2169-5202</identifier><identifier>DOI: 10.1177/1550059420979250</identifier><identifier>PMID: 33289577</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Anisotropy ; Brain - diagnostic imaging ; Diffusion Tensor Imaging ; Electroencephalography ; Hemifacial Spasm - diagnostic imaging ; Humans ; Magnetic resonance imaging ; Middle Aged ; Myelination ; Neuroimaging ; Sleep Quality ; Statistical analysis ; Substantia alba ; Visual perception ; White Matter - diagnostic imaging</subject><ispartof>Clinical EEG and neuroscience, 2022-03, Vol.53 (2), p.165-172</ispartof><rights>EEG and Clinical Neuroscience Society (ECNS) 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c365t-4a4c6051722ed2811815286146c0b6aa64e45c20ec704071022e83af9855f6e43</citedby><cites>FETCH-LOGICAL-c365t-4a4c6051722ed2811815286146c0b6aa64e45c20ec704071022e83af9855f6e43</cites><orcidid>0000-0001-7199-5672</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/1550059420979250$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/1550059420979250$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,21819,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33289577$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Jian</creatorcontrib><creatorcontrib>Yu, Qingyang</creatorcontrib><creatorcontrib>Gu, Peng</creatorcontrib><creatorcontrib>Sun, Hongtao</creatorcontrib><creatorcontrib>Yuan, Fei</creatorcontrib><creatorcontrib>Zhang, Quan</creatorcontrib><title>Brain Structure Alterations in Hemifacial Spasm: A Diffusion Tensor Imaging Study</title><title>Clinical EEG and neuroscience</title><addtitle>Clin EEG Neurosci</addtitle><description>This study examined white matter integrity in patients with left-sided hemifacial spasm (HFS) using diffusion tensor imaging (DTI). Thirty-six patients with left-sided HFS (mean age 53.24 ± 8.16 years) and 36 healthy volunteers (mean age 53.92 ± 7.73 years) were recruited. Tract-based spatial statistics (TBSS) analysis revealed significantly increased fractional anisotropy (FA) of bilateral superior longitudinal fasciculus in HFS patients (P < 0.05, family-wise error corrected), with trends for radial diffusivity to decrease. We inferred that the results may be associated with poor sleep quality, impairment in visuospatial construction, and activity-dependent increases in myelination in HFS patients. Furthermore, the FA value of left superior longitudinal fasciculus showed a positive correlation with HFS duration (r = 0.352, P = .041) and spasm severity (r = 0.416, P = .014). However, the alteration of medial diffusivity and axial diffusivity were not found in bilateral superior longitudinal fasciculus between groups. These findings suggest FA changes of superior longitudinal fasciculus reflected by TBSS analysis may provide valuable insights into the diagnosis of HFS.</description><subject>Anisotropy</subject><subject>Brain - diagnostic imaging</subject><subject>Diffusion Tensor Imaging</subject><subject>Electroencephalography</subject><subject>Hemifacial Spasm - diagnostic imaging</subject><subject>Humans</subject><subject>Magnetic resonance imaging</subject><subject>Middle Aged</subject><subject>Myelination</subject><subject>Neuroimaging</subject><subject>Sleep Quality</subject><subject>Statistical analysis</subject><subject>Substantia alba</subject><subject>Visual perception</subject><subject>White Matter - diagnostic imaging</subject><issn>1550-0594</issn><issn>2169-5202</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kEtLAzEURoMotlb3riTgxs3ozXvGXa2PFgoireshTTNlyjxqMln035vSqlBwdRffud-9HISuCdwTotQDEQJAZJxCpjIq4AT1KZFZIijQU9Tfxcku76EL79cATFLGz1GPMZpmQqk--nhyumzwrHPBdMFZPKw663RXto3HMRjbuiy0KXWFZxvt60c8xM9lUQQfCTy3jW8dntR6VTar2BKW20t0VujK26vDHKDP15f5aJxM398mo-E0MUyKLuGaGwmCKErtkqaEpETQVBIuDSyk1pJbLgwFaxRwUAQilzJdZKkQhbScDdDdvnfj2q9gfZfXpTe2qnRj2-BzymXKGBMqi-jtEbpug2vidzmVURhQLlSkYE8Z13rvbJFvXFlrt80J5Dvd-bHuuHJzKA6L2i5_F378RiDZA16v7N_Vfwu_AeCshA4</recordid><startdate>202203</startdate><enddate>202203</enddate><creator>Zhang, Jian</creator><creator>Yu, Qingyang</creator><creator>Gu, Peng</creator><creator>Sun, Hongtao</creator><creator>Yuan, Fei</creator><creator>Zhang, Quan</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>4T-</scope><scope>7TK</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7199-5672</orcidid></search><sort><creationdate>202203</creationdate><title>Brain Structure Alterations in Hemifacial Spasm: A Diffusion Tensor Imaging Study</title><author>Zhang, Jian ; Yu, Qingyang ; Gu, Peng ; Sun, Hongtao ; Yuan, Fei ; Zhang, Quan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-4a4c6051722ed2811815286146c0b6aa64e45c20ec704071022e83af9855f6e43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Anisotropy</topic><topic>Brain - diagnostic imaging</topic><topic>Diffusion Tensor Imaging</topic><topic>Electroencephalography</topic><topic>Hemifacial Spasm - diagnostic imaging</topic><topic>Humans</topic><topic>Magnetic resonance imaging</topic><topic>Middle Aged</topic><topic>Myelination</topic><topic>Neuroimaging</topic><topic>Sleep Quality</topic><topic>Statistical analysis</topic><topic>Substantia alba</topic><topic>Visual perception</topic><topic>White Matter - diagnostic imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Jian</creatorcontrib><creatorcontrib>Yu, Qingyang</creatorcontrib><creatorcontrib>Gu, Peng</creatorcontrib><creatorcontrib>Sun, Hongtao</creatorcontrib><creatorcontrib>Yuan, Fei</creatorcontrib><creatorcontrib>Zhang, Quan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Docstoc</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical EEG and neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Jian</au><au>Yu, Qingyang</au><au>Gu, Peng</au><au>Sun, Hongtao</au><au>Yuan, Fei</au><au>Zhang, Quan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Brain Structure Alterations in Hemifacial Spasm: A Diffusion Tensor Imaging Study</atitle><jtitle>Clinical EEG and neuroscience</jtitle><addtitle>Clin EEG Neurosci</addtitle><date>2022-03</date><risdate>2022</risdate><volume>53</volume><issue>2</issue><spage>165</spage><epage>172</epage><pages>165-172</pages><issn>1550-0594</issn><eissn>2169-5202</eissn><abstract>This study examined white matter integrity in patients with left-sided hemifacial spasm (HFS) using diffusion tensor imaging (DTI). Thirty-six patients with left-sided HFS (mean age 53.24 ± 8.16 years) and 36 healthy volunteers (mean age 53.92 ± 7.73 years) were recruited. Tract-based spatial statistics (TBSS) analysis revealed significantly increased fractional anisotropy (FA) of bilateral superior longitudinal fasciculus in HFS patients (P < 0.05, family-wise error corrected), with trends for radial diffusivity to decrease. We inferred that the results may be associated with poor sleep quality, impairment in visuospatial construction, and activity-dependent increases in myelination in HFS patients. Furthermore, the FA value of left superior longitudinal fasciculus showed a positive correlation with HFS duration (r = 0.352, P = .041) and spasm severity (r = 0.416, P = .014). However, the alteration of medial diffusivity and axial diffusivity were not found in bilateral superior longitudinal fasciculus between groups. These findings suggest FA changes of superior longitudinal fasciculus reflected by TBSS analysis may provide valuable insights into the diagnosis of HFS.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>33289577</pmid><doi>10.1177/1550059420979250</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-7199-5672</orcidid></addata></record> |
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| subjects | Anisotropy Brain - diagnostic imaging Diffusion Tensor Imaging Electroencephalography Hemifacial Spasm - diagnostic imaging Humans Magnetic resonance imaging Middle Aged Myelination Neuroimaging Sleep Quality Statistical analysis Substantia alba Visual perception White Matter - diagnostic imaging |
| title | Brain Structure Alterations in Hemifacial Spasm: A Diffusion Tensor Imaging Study |
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