The Impression of a Nonexisting Catalytic Effect: The Role of CotB2 in Guiding the Complex Biosynthesis of Cyclooctat-9-en-7-ol

Terpene synthases generate terpenes employing diversified carbocation chemistry, including highly specific ring formations, proton and hydride transfers, and methyl as well as methylene migrations, followed by reaction quenching. In this enzyme family, the main catalytic challenge is not rate enhanc...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of the American Chemical Society 2020-12, Vol.142 (51), p.21562-21574
Hauptverfasser:	Raz, Keren, Driller, Ronja, Dimos, Nicole, Ringel, Marion, Brück, Thomas, Loll, Bernhard, Major, Dan Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkyl and Aryl Transferases - chemistry Alkyl and Aryl Transferases - metabolism Biocatalysis Cyclooctanes - chemistry Cyclooctanes - metabolism Models, Molecular Protein Conformation Quantum Theory
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!