In vitro and in vivo comparative performance studies of gadolinium‐loaded zeolites and Gd‐DOTA as contrast agents for MRI applications

Gadolinium‐based contrast agents (CAs) were synthesized using faujasite zeolite (NaX) and zeolite beta (BEA) and their performances in vitro and in vivo were compared to the widely used commercial CA, gadoteric acid (Gd‐DOTA). Magnetic resonance imaging (MRI) relaxometry studies (considering longitu...

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Veröffentlicht in:	Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2021-08, Vol.109 (8), p.1105-1115
Hauptverfasser:	Contro, Janine, Silva, Danilo Antonio, Santisteban, Oscar A. N., Narayana, Ponnada A., Nery, José G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiography Animals Biomedical materials contrast agent Contrast agents Contrast media Contrast Media - chemistry Contrast Media - pharmacokinetics Contrast Media - pharmacology Diameters Female Gadolinium Gadolinium - chemistry Gadolinium - pharmacokinetics Gadolinium - pharmacology Gd‐DOTA Heterocyclic Compounds - chemistry Heterocyclic Compounds - pharmacokinetics Heterocyclic Compounds - pharmacology Image contrast In vivo methods and tests Magnetic Resonance Imaging Materials research Materials science Organometallic Compounds - chemistry Organometallic Compounds - pharmacokinetics Organometallic Compounds - pharmacology Rats Rats, Sprague-Dawley relaxivity zeolite Zeolites Zeolites - chemistry Zeolites - pharmacokinetics Zeolites - pharmacology
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