Reprint of: Role of O-linked N-acetylglucosamine (O-GlcNAc) modification of proteins in diabetic cardiovascular complications

The post-translational modification of serine and threonine residues of proteins by O-linked N-acetylglucosamine (O-GlcNAc) regulates diverse cellular processes in the cardiovascular system. UDP-GlcNAc is a substrate for O-GlcNAc transferase, which catalyzes the attachment of O-GlcNAc to proteins. O...

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Veröffentlicht in:Current opinion in pharmacology 2020-10, Vol.54, p.209-220
Hauptverfasser: Chatham, John C., Young, Martin E., Zhang, Jianhua
Format: Artikel
Sprache:eng
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