Local blood coagulation drives cancer cell arrest and brain metastasis in a mouse model

Clinically relevant brain metastases (BMs) frequently form in cancer patients, with limited options for effective treatment. Circulating cancer cells must first permanently arrest in brain microvessels to colonize the brain, but the critical factors in this process are not well understood. Here, in...

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Veröffentlicht in:	Blood 2021-03, Vol.137 (9), p.1219-1232
Hauptverfasser:	Feinauer, Manuel J., Schneider, Stefan W., Berghoff, Anna S., Robador, Jose Ramon, Tehranian, Cedric, Karreman, Matthia A., Venkataramani, Varun, Solecki, Gergely, Grosch, Julia Katharina, Gunkel, Katharina, Kovalchuk, Bogdana, Mayer, Frank Thomas, Fischer, Manuel, Breckwoldt, Michael O., Brune, Maik, Schwab, Yannick, Wick, Wolfgang, Bauer, Alexander T., Winkler, Frank
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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