Development and Validation of an RNA Sequencing Assay for Gene Fusion Detection in Formalin-Fixed, Paraffin-Embedded Tumors

RNA sequencing (RNA-seq) is a well-validated tool for detecting gene fusions in fresh-frozen tumors; however, RNA-seq is much more challenging to use with formalin-fixed, paraffin-embedded (FFPE) tumor samples. We evaluated the performance of RNA-seq to detect gene fusions in clinical FFPE tumor sam...

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Veröffentlicht in:	The Journal of molecular diagnostics : JMD 2021-02, Vol.23 (2), p.223-233
Hauptverfasser:	Peng, Hao, Huang, Rong, Wang, Kui, Wang, Cuiyun, Li, Bin, Guo, Youbing, Li, Meng, Zhang, Dadong, Dong, Hua, Chen, Hao, Chen, Caifu, Xu, Qing, Li, Fugen, Tian, Lei, Wu, Jianbing
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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