A Monte Carlo method to estimate cell population heterogeneity from cell snapshot data

•Determining sources of cellular variation is crucial for a range of applications.•A statistical method for determining cellular variation from snapshot data is given.•The method is Bayesian and most applicable when measurement noise is small.•The power of the method is illustrated for four biologic...

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Veröffentlicht in:	Journal of theoretical biology 2021-02, Vol.511, p.110541-110541, Article 110541
Hauptverfasser:	Lambert, Ben, Gavaghan, David J., Tavener, Simon J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bayesian inference Cellular heterogeneity Inverse problems Single cell data
Online-Zugang:	Volltext
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