Tumor microenvironment triple-responsive nanoparticles enable enhanced tumor penetration and synergetic chemo-photodynamic therapy

A novel combined chemo/photodynamic therapy has been developed to use pH/ROS/MMP-2 triple-responsive drug nanocarriers for treating solid tumor with an extraordinarily high efficiency. The designed poly(ethylene glycol)-peptide-poly(ω-pentadecalactone-co-N-methyldiethyleneamine-co-3,3′-thiodipropion...

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Veröffentlicht in:	Biomaterials 2021-01, Vol.268, p.120574-120574, Article 120574
Hauptverfasser:	Shu, Man, Tang, Junjie, Chen, Lili, Zeng, Qiang, Li, Chao, Xiao, Shuting, Jiang, Zhaozhong, Liu, Jie
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug delivery MMP-2 Nanoparticles pH and ROS-Responsive Photodynamic therapy ROS amplification
Online-Zugang:	Volltext
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