Platelets Stimulate Liver Regeneration in a Rat Model of Partial Liver Transplantation

Living donor liver transplantation (LDLT) is sometimes associated with impaired regeneration and severe ischemia/reperfusion injury (IRI) in the graft, resulting in small‐for‐size syndrome (SFSS). Platelets were previously reported to stimulate liver regeneration in models of hepatectomy, but the ev...

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Veröffentlicht in:	Liver transplantation 2021-05, Vol.27 (5), p.719-734
Hauptverfasser:	Liang, Chen, Takahashi, Kazuhiro, Furuya, Kinji, Oda, Tatsuya, Ohkohchi, Nobuhiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Ascites Bilirubin Blood Platelets Body weight Growth factors Hepatectomy Hepatocyte growth factor Humans Insulin Interleukin 6 Ischemia Labeling Liver Liver Regeneration Liver transplantation Liver Transplantation - adverse effects Liver transplants Living Donors Oxidative stress Platelets Proliferating cell nuclear antigen Rats Reperfusion Serum levels Signal transduction Thrombocytosis Thrombopoietin Tumor necrosis factor-TNF Tumor necrosis factor-α
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