Analysis of the Efficiency of Different Antituberculous Drugs and Approaches to Treat BCG-Induced Granulomatosis in Mice and Abundance and Localization of Mycobacterium tuberculosis in the Liver

In 3 months after infection with Mycobacterium tuberculosis (MBT) from BCG vaccine, male BALB/с mice received intraperitoneal injections of isonicotinic acid hydrazide, dextrazide, or liposome-encapsulated dextrazide, or inhalation of liposome-encapsulated dextrazide 2 times a week for 6 months. In...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2020-12, Vol.170 (2), p.233-235
Hauptverfasser:	Sinyavskaya, A. M., Shkurupy, V. A., Troitskii, A. V., Kovner, A. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antitubercular agents Bacillus Calmette-Guerin vaccine BCG BCG vaccines Biomedical and Life Sciences Biomedicine Cell Biology Drug therapy Granuloma Granulomas Granulomatosis Health aspects Inhalation Internal Medicine Laboratory Medicine Leukocyte migration Liver Localization Lysosomes Macrophages Mycobacterium tuberculosis Parenchyma Pathology Tuberculosis Vaccines
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