Ionic dissolution products of Cerium-doped bioactive glass nanoparticles promote cellular osteogenic differentiation and extracellular matrix formation of human bone marrow derived mesenchymal stromal cells

Cerium (Ce) is a promising candidate ion for application in bone tissue engineering (BTE) since it reduces the presence of reactive oxygen species. Ce-doped mesoporous bioactive glass nanoparticles (MBGNs) serving as vectors for the local application of Ce already demonstrated stimulating effects on...

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Veröffentlicht in:	Biomedical materials (Bristol) 2021-05, Vol.16 (3), p.35028
Hauptverfasser:	Westhauser, F, Rehder, F, Decker, S, Kunisch, E, Moghaddam, A, Zheng, K, Boccaccini, A R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biocompatible Materials - chemistry Biocompatible Materials - pharmacology Bone and Bones - cytology Bone and Bones - metabolism Cell Differentiation - drug effects Cells, Cultured Cerium - chemistry Cerium - metabolism Extracellular Matrix - drug effects Extracellular Matrix - metabolism Glass - chemistry Humans Male Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - drug effects Nanoparticles - chemistry Nanoparticles - metabolism Osteogenesis - drug effects Tissue Engineering - methods Young Adult
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