Expression levels of miR‐27a, miR‐329, ABCA1, and ABCG1 genes in peripheral blood mononuclear cells and their correlation with serum levels of oxidative stress and hs‐CRP in the patients with coronary artery disease

Atherosclerosis is a chronic inflammatory disease with high mortality worldwide. The reverse cholesterol transport pathway in macrophage plays an important role in the pathogenesis of coronary artery disease (CAD) and is strongly controlled by regulatory factors. The microRNAs can promote or prevent...

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Veröffentlicht in:	IUBMB life 2021-01, Vol.73 (1), p.223-237
Hauptverfasser:	Rafiei, Ali, Ferns, Gordon A., Ahmadi, Reza, Khaledifar, Arsalan, Rahimzadeh‐Fallah, Tina, Mohmmad‐Rezaei, Mina, Emami, Shohreh, Bagheri, Nader
Format:	Artikel
Sprache:	eng
Schlagworte:	ABCA1 ABCA1 protein ABCG1 ABCG1 gene Adult Antioxidants Arteriosclerosis Atherosclerosis Atherosclerosis - blood Atherosclerosis - genetics Atherosclerosis - metabolism Atherosclerosis - pathology ATP Binding Cassette Transporter 1 - blood ATP Binding Cassette Transporter 1 - genetics ATP Binding Cassette Transporter, Subfamily G, Member 1 - blood ATP Binding Cassette Transporter, Subfamily G, Member 1 - genetics ATP-binding protein C-Reactive Protein - analysis Cardiovascular disease Case-Control Studies Cholesterol Chromosome 3 Coronary artery Coronary Artery Disease - blood Coronary Artery Disease - genetics Coronary Artery Disease - metabolism Coronary Artery Disease - pathology Coronary vessels Enzyme-linked immunosorbent assay Female Gene expression Gene Expression Regulation Gene regulation Heart diseases hs‐CRP Humans Inflammatory diseases Leukocytes (mononuclear) Leukocytes, Mononuclear - metabolism Leukocytes, Mononuclear - pathology Low density lipoprotein Macrophages Male Malondialdehyde microRNA MicroRNAs - blood MicroRNAs - genetics miRNA Oxidative Stress Peripheral blood mononuclear cells Serum levels Transcription
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