Beneficial effects of autologous mesenchymal stem cell transplantation in active progressive multiple sclerosis

In this study (trial registration: NCT02166021), we aimed to evaluate the optimal way of administration, the safety and the clinical efficacy of mesenchymal stem cell (MSC) transplantation in patients with active and progressive multiple sclerosis. Forty-eight patients (28 males and 20 females) with...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2020-12, Vol.143 (12), p.3574-3588
Hauptverfasser:	Petrou, Panayiota, Kassis, Ibrahim, Levin, Netta, Paul, Friedemann, Backner, Yael, Benoliel, Tal, Oertel, Frederike Cosima, Scheel, Michael, Hallimi, Michelle, Yaghmour, Nour, Hur, Tamir Ben, Ginzberg, Ariel, Levy, Yarden, Abramsky, Oded, Karussis, Dimitrios
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Brain - diagnostic imaging Disease Progression Double-Blind Method Endpoint Determination Female Follow-Up Studies Humans Injections, Intravenous Injections, Spinal Magnetic Resonance Imaging Male Mesenchymal Stem Cell Transplantation - adverse effects Mesenchymal Stem Cell Transplantation - methods Middle Aged Multiple Sclerosis - diagnostic imaging Multiple Sclerosis - psychology Multiple Sclerosis - therapy Multiple Sclerosis, Chronic Progressive - therapy Neuropsychological Tests Recurrence Tomography, Optical Coherence Treatment Outcome Walking
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