Pancreatic cancer-targeting exosomes for enhancing immunotherapy and reprogramming tumor microenvironment

Immunotherapy has gained increasing focus in treating pancreatic ductal adenocarcinoma (PDAC), since conventional therapies like chemotherapy could not provide satisfactory improvement in overall survival outcome of PDAC patients. However, it is still not the game changing solution due to the unique...

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Veröffentlicht in:	Biomaterials 2021-01, Vol.268, p.120546-120546, Article 120546
Hauptverfasser:	Zhou, Wenxi, Zhou, Yu, Chen, Xinli, Ning, Tingting, Chen, Hongyi, Guo, Qin, Zhang, Yiwen, Liu, Peixin, Zhang, Yujie, Li, Chao, Chu, Yongchao, Sun, Tao, Jiang, Chen
Format:	Artikel
Sprache:	eng
Schlagworte:	BM-MSC exosomes Galectin 9/dectin 1 axis Immunogenic cell death Macrophage polarization Pancreatic cancer immunotherapy
Online-Zugang:	Volltext
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