Evaluation of bovine milk extracellular vesicles for the delivery of locked nucleic acid antisense oligonucleotides

[Display omitted] The natural capacity of extracellular vesicles (EVs) to transport their payload to recipient cells has raised big interest to repurpose EVs as delivery vehicles for xenobiotics. In the present study, bovine milk-derived EVs (BMEVs) were investigated for their potential to shuttle l...

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Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2021-01, Vol.158, p.198-210
Hauptverfasser:	Grossen, Philip, Portmann, Michaela, Koller, Erich, Duschmalé, Martina, Minz, Tanja, Sewing, Sabine, Pandya, Nikhil Janak, van Geijtenbeek, Sabine Kux, Ducret, Axel, Kusznir, Eric-André, Huber, Sylwia, Berrera, Marco, Lauer, Matthias E., Ringler, Philippe, Nordbo, Bettina, Jensen, Marianne Lerbech, Sladojevich, Filippo, Jagasia, Ravi, Alex, Rainer, Gamboni, Remo, Keller, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Antisense oligonucleotide Bovine milk Drug delivery Exosomes Extracellular vesicles Oral drug delivery
Online-Zugang:	Volltext
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