Linoleic acid induces secretion of extracellular vesicles from MDA-MB-231 breast cancer cells that mediate cellular processes involved with angiogenesis in HUVECs

[Display omitted] •Extracellular vesicles from breast cancer cells mediate angiogenesis.•Linoleic acid induces release of angiogenic extracellular vesicles.•FFAR1 and FFAR4 mediate the release of angiogenic extracellular vesicles. Extracellular vesicles (EVs) are vesicles secreted by normal and mali...

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Veröffentlicht in:	Prostaglandins & other lipid mediators 2021-04, Vol.153, p.106519, Article 106519
Hauptverfasser:	Garcia-Hernandez, Alejandra, Leal-Orta, Elizabeth, Ramirez-Ricardo, Javier, Cortes-Reynosa, Pedro, Thompson-Bonilla, Rocio, Salazar, Eduardo Perez
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Breast cancer Breast Neoplasms - metabolism Breast Neoplasms - pathology Cell Line, Tumor Cell Movement - drug effects Cell Proliferation - drug effects Extracellular vesicles Extracellular Vesicles - metabolism Female Human Umbilical Vein Endothelial Cells - drug effects Human Umbilical Vein Endothelial Cells - metabolism Humans HUVECs Linoleic acid Linoleic Acid - pharmacology Matrix Metalloproteinase 9 - metabolism MDA-MB-231 Neovascularization, Pathologic - metabolism Receptors, G-Protein-Coupled - metabolism
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