Assessment of Aptamer-Targeted Contrast Agents for Monitoring of Blood Clots in Computed Tomography and Fluoroscopy Imaging

Objective: Random formation of thrombi is classified as a pathological process that may result in partial or complete obstruction of blood flow and limited perfusion. Further complications include pulmonary embolism, thrombosis-induced myocardial infraction, ischemic stroke, and others. Location and...

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Veröffentlicht in:	Bioconjugate chemistry 2020-12, Vol.31 (12), p.2737-2749
Hauptverfasser:	Koudrina, Anna, O’Brien, Jonathan, Garcia, Roberto, Boisjoli, Spencer, Kan, Peter T. M, Tsai, Eve C, DeRosa, Maria C
Format:	Artikel
Sprache:	eng
Schlagworte:	Aptamers Binding Blood clots Blood coagulation Blood flow Calorimetry Carotid artery Complications Computed tomography Contrast agents Contrast media Delineation Embolism Fibrin Fibrinogen Fluoroscopy Gold Iodine Ischemia Livestock Nanoparticles Perfusion Swine Thromboembolism Thrombosis Titration Titration calorimetry
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