Immunophenotypic analysis of lymphocyte subsets in newborns with biotinidase deficiency

Background/Aim Biotin is a vital micronutrient that plays a role in metabolic homeostasis and the regulation of innate and adaptive immune system functions. Biotinidase deficiency (BTD) leads to impairment in biotin‐dependent immune functions. This study focused on immunophenotypic analysis of lymph...

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Veröffentlicht in:	Pediatric allergy and immunology 2021-04, Vol.32 (3), p.586-598
Hauptverfasser:	Karaoglan, Murat, Nacarkahya, Gulper, Keskin, Mehmet, Keskin, Ozlem, Atanaskovic‐Markovic, Marina
Format:	Artikel
Sprache:	eng
Schlagworte:	Biotin Biotinidase biotinidase deficiency CD16 antigen CD19 antigen CD3 antigen CD4 antigen CD8 antigen Cell activation Cytotoxicity Enzymatic activity Females Histocompatibility antigen HLA Homeostasis Immune system lymphocyte immunophenotyping Lymphocytes Lymphocytes B Lymphocytes T Males Neonates Phenotypes Sexual dimorphism sexual immune dimorphism
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