Inactivated Four-Factor Prothrombin Complex Concentrate Dosing Practices for Reversal of Warfarin-Related Intracranial Hemorrhage

Background/Objective Inactivated four-factor prothrombin complex concentrate (I4F-PCC, Kcentra ® ) has become an important agent for the urgent or emergent reversal of bleeding associated with vitamin K antagonists such as warfarin. There is recognized inter-institutional variability with the use of...

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Veröffentlicht in:	Neurocritical care 2021-08, Vol.35 (1), p.130-138
Hauptverfasser:	Rhoney, Denise H., La, Mary, Merz, Molly, Cook, Aaron, Owusu, Kent A., Roels, Christina, Blunck, Joe, Shewmaker, Justin, Sangha, Kiranpal S., Farrokh, Salia, Lewin, John, Chester, Kathleen W., Human, Theresea, Bledsoe, Kathleen, Greene, Kristy, Levesque, Melissa, Rocker, Jody C., Davis, Gary, Neyens, Ron, Lassiter, Timothy F., Adriance, Sarah M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anticoagulants Anticoagulants - adverse effects Blood Coagulation Factors Cardiac arrhythmia Critical Care Medicine Descriptive labeling Diabetes Drug dosages Heart failure Hemorrhage Humans Intensive Internal Medicine International Normalized Ratio Intracranial Hemorrhages - chemically induced Intracranial Hemorrhages - drug therapy Medicine Medicine & Public Health Mortality Neurology Neurosurgery Original Work Patients Retrospective Studies Stroke Thromboembolism Warfarin - adverse effects
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