Maresin 1 regulates insulin signaling in human adipocytes as well as in adipose tissue and muscle of lean and obese mice

Maresin 1 (MaR1) is a DHA-derived pro-resolving lipid mediator. The present study aimed to characterize the ability of MaR1 to prevent the alterations induced by TNF-α on insulin actions in glucose uptake and Akt phosphorylation in cultured human adipocytes from overweight/obese subjects, as well as...

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Veröffentlicht in:	Journal of physiology and biochemistry 2021-02, Vol.77 (1), p.167-173
Hauptverfasser:	Martínez-Fernández, L., González-Muniesa, P., Sáinz, N., Escoté, X., Martínez, J. A., Arbones-Mainar, J. M., Moreno-Aliaga, M. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipose tissue AKT protein Animal Physiology Biomedical and Life Sciences Biomedicine Body weight Cytokines Diet Glucose High fat diet Human Physiology Hyperglycemia Inflammation Insulin Insulin resistance Lipids Muscles Musculoskeletal system Obesity Original Article Overweight Phosphorylation Signaling Skeletal muscle Tumor necrosis factor-α
Online-Zugang:	Volltext
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