A photoactivatable Ru (II) complex bearing 2,9-diphenyl-1,10-phenanthroline: A potent chemotherapeutic drug inducing apoptosis in triple negative human breast adenocarcinoma cells

The photoactivatable Ru (II) complex 1 [Ru(bipy)2(dpphen)]Cl2 (where bipy = 2,2′-bipyridine and dpphen = 2,9-diphenyl-1,10-phenanthroline) has been shown to possess promising anticancer activity against triple negative adenocarcinoma MDA-MB-231 cells. The present study aims to elucidate the plausibl...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chemico-biological interactions 2021-02, Vol.336, p.109317-109317, Article 109317
Hauptverfasser:	Mansour, Najwa, Bodman-Smith, Kikki, Khnayzer, Rony S., Daher, Costantine F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Anticancer Antineoplastic Agents - chemical synthesis Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Apoptosis - drug effects Breast cancer Cell Proliferation - drug effects Cell Survival - drug effects Coordination Complexes - chemical synthesis Coordination Complexes - chemistry Coordination Complexes - pharmacology Drug Screening Assays, Antitumor Humans MDA-MB-231 Phenanthrolines - chemistry Phenanthrolines - pharmacology Photoactivatable chemotherapy Photochemical Processes Ruthenium - chemistry Ruthenium - pharmacology Ruthenium complexes Triple Negative Breast Neoplasms - drug therapy Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!