Strictly Lobar Microbleeds Reflect Amyloid Angiopathy Regardless of Cerebral and Cerebellar Compartments
BACKGROUND AND PURPOSE:We aimed to determine whether lobar cerebellar microbleeds or concomitant lobar cerebellar and deep microbleeds, in the presence of lobar cerebral microbleeds, attribute to underlying advanced cerebral amyloid angiopathy pathology or hypertensive arteriopathy. METHODS:We categ...
Gespeichert in:
| Veröffentlicht in: | Stroke (1970) 2020-12, Vol.51 (12), p.3600-3607 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 3607 |
|---|---|
| container_issue | 12 |
| container_start_page | 3600 |
| container_title | Stroke (1970) |
| container_volume | 51 |
| creator | Jung, Young Hee Jang, Hyemin Park, Seong Beom Choe, Yeong Sim Park, Yuhyun Kang, Sung Hoon Lee, Jong Min Kim, Ji Sun Kim, Jaeho Kim, Jun Pyo Kim, Hee Jin Na, Duk L. Seo, Sang Won |
| description | BACKGROUND AND PURPOSE:We aimed to determine whether lobar cerebellar microbleeds or concomitant lobar cerebellar and deep microbleeds, in the presence of lobar cerebral microbleeds, attribute to underlying advanced cerebral amyloid angiopathy pathology or hypertensive arteriopathy.
METHODS:We categorized 71 patients with suspected cerebral amyloid angiopathy markers (regardless of the presence of deep and cerebellar microbleeds) into 4 groups according to microbleed distributionL (strictly lobar cerebral, n=33), L/LCbll (strictly lobar cerebral and strictly lobar cerebellar microbleeds, n=13), L/Cbll/D (lobar, cerebellar, and deep microbleeds, n=17), and L/D (lobar and deep, n=8). We additionally categorized patients with cerebellar microbleeds into 2 groups according to dentate nucleus involvementstrictly lobar cerebellar (n=16) and dentate (n=14). We then compared clinical characteristics, Aβ (amyloid-β) positivity on PET (positron emission tomography), magnetic resonance imaging cerebral amyloid angiopathy markers, and cerebral small vessel disease burden among groups.
RESULTS:The frequency of Aβ positivity was higher in the L and L/LCbll groups (81.8% and 84.6%) than in the L/Cbll/D and L/D groups (37.5% and 29.4%; P |
| doi_str_mv | 10.1161/STROKEAHA.119.028487 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2461391529</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2461391529</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4677-917272313361a17becd5e1203aa5885cbcb61b0335236fbc2631b843d3df5bc23</originalsourceid><addsrcrecordid>eNqFkc1u1DAUhS0EotPCGyCUJZuU65849jIaFYo6qFJb1pHt3HQCzniwParm7fEopUtYWUc-5_j6u4R8oHBJqaSf7x_ubm-uuuuuSH0JTAnVviIr2jBRC8nUa7IC4LpmQuszcp7STwBgXDVvyRnnVKtGwYps73OcXPbHahOsidX3ycVgPeKQqjscPbpcdfPRh2mout3jFPYmb4_l6tHEwWNKVRirNUa00fjK7IZFoPelbB3mvYl5xl1O78ib0fiE75_PC_Ljy9XD-rre3H79tu42tROybWtNW9YyTjmX1NDWohsapAy4MY1SjbPOSmqB84ZxOVrHJKdWCT7wYWyK5Bfk09K7j-H3AVPu5ym50zw7DIfUMyEp14WSLlaxWMuXU4o49vs4zSYeewr9iXH_wrhI3S-MS-zj8wsHO-PwEvoLtRjUYngKPmNMv_zhCWO_RePz9n_d4h_RskBoZQs1AwYFCkB92inlfwCWVJpa</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2461391529</pqid></control><display><type>article</type><title>Strictly Lobar Microbleeds Reflect Amyloid Angiopathy Regardless of Cerebral and Cerebellar Compartments</title><source>Journals@Ovid Ovid Autoload</source><source>MEDLINE</source><source>American Heart Association Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Jung, Young Hee ; Jang, Hyemin ; Park, Seong Beom ; Choe, Yeong Sim ; Park, Yuhyun ; Kang, Sung Hoon ; Lee, Jong Min ; Kim, Ji Sun ; Kim, Jaeho ; Kim, Jun Pyo ; Kim, Hee Jin ; Na, Duk L. ; Seo, Sang Won</creator><creatorcontrib>Jung, Young Hee ; Jang, Hyemin ; Park, Seong Beom ; Choe, Yeong Sim ; Park, Yuhyun ; Kang, Sung Hoon ; Lee, Jong Min ; Kim, Ji Sun ; Kim, Jaeho ; Kim, Jun Pyo ; Kim, Hee Jin ; Na, Duk L. ; Seo, Sang Won</creatorcontrib><description>BACKGROUND AND PURPOSE:We aimed to determine whether lobar cerebellar microbleeds or concomitant lobar cerebellar and deep microbleeds, in the presence of lobar cerebral microbleeds, attribute to underlying advanced cerebral amyloid angiopathy pathology or hypertensive arteriopathy.
METHODS:We categorized 71 patients with suspected cerebral amyloid angiopathy markers (regardless of the presence of deep and cerebellar microbleeds) into 4 groups according to microbleed distributionL (strictly lobar cerebral, n=33), L/LCbll (strictly lobar cerebral and strictly lobar cerebellar microbleeds, n=13), L/Cbll/D (lobar, cerebellar, and deep microbleeds, n=17), and L/D (lobar and deep, n=8). We additionally categorized patients with cerebellar microbleeds into 2 groups according to dentate nucleus involvementstrictly lobar cerebellar (n=16) and dentate (n=14). We then compared clinical characteristics, Aβ (amyloid-β) positivity on PET (positron emission tomography), magnetic resonance imaging cerebral amyloid angiopathy markers, and cerebral small vessel disease burden among groups.
RESULTS:The frequency of Aβ positivity was higher in the L and L/LCbll groups (81.8% and 84.6%) than in the L/Cbll/D and L/D groups (37.5% and 29.4%; P<0.001), while lacune numbers were lower in the L and L/LCbll groups (1.7±3.3 and 1.7±2.6) than in the L/Cbll/D and L/D groups (8.0±10.3 and 13.4±17.7, P=0.001). The L/LCbll group had more lobar cerebral microbleeds than the L group (93.2±121.8 versus 38.0±40.8, P=0.047). The lobar cerebellar group had a higher Aβ positivity (75% versus 28.6%, P=0.011) and lower lacune number (2.3±3.7 versus 8.6±1.2, P=0.041) than the dentate group.
CONCLUSIONS:Strictly lobar cerebral and cerebellar microbleeds are related to cerebral amyloid angiopathy, whereas any combination of concurrent lobar and deep microbleeds suggest hypertensive angiopathy regardless of cerebral or cerebellar compartments.</description><identifier>ISSN: 0039-2499</identifier><identifier>EISSN: 1524-4628</identifier><identifier>DOI: 10.1161/STROKEAHA.119.028487</identifier><identifier>PMID: 33198580</identifier><language>eng</language><publisher>United States: American Heart Association, Inc</publisher><subject>Aged ; Aged, 80 and over ; Aniline Compounds ; Basal Ganglia Hemorrhage - diagnostic imaging ; Benzothiazoles ; Cerebellar Diseases - diagnostic imaging ; Cerebellar Nuclei - diagnostic imaging ; Cerebellum - diagnostic imaging ; Cerebral Amyloid Angiopathy - diagnostic imaging ; Cerebral Hemorrhage - diagnostic imaging ; Cerebral Small Vessel Diseases - diagnostic imaging ; Cognitive Dysfunction - diagnostic imaging ; Dementia - diagnostic imaging ; Female ; Humans ; Intracranial Hemorrhages - diagnostic imaging ; Magnetic Resonance Imaging ; Male ; Positron-Emission Tomography ; Radiopharmaceuticals ; Stilbenes ; Thalamic Diseases - diagnostic imaging ; Thiazoles</subject><ispartof>Stroke (1970), 2020-12, Vol.51 (12), p.3600-3607</ispartof><rights>American Heart Association, Inc.</rights><rights>2020 American Heart Association, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4677-917272313361a17becd5e1203aa5885cbcb61b0335236fbc2631b843d3df5bc23</citedby><cites>FETCH-LOGICAL-c4677-917272313361a17becd5e1203aa5885cbcb61b0335236fbc2631b843d3df5bc23</cites><orcidid>0000-0002-8747-0122 ; 0000-0003-3152-1274</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3674,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33198580$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jung, Young Hee</creatorcontrib><creatorcontrib>Jang, Hyemin</creatorcontrib><creatorcontrib>Park, Seong Beom</creatorcontrib><creatorcontrib>Choe, Yeong Sim</creatorcontrib><creatorcontrib>Park, Yuhyun</creatorcontrib><creatorcontrib>Kang, Sung Hoon</creatorcontrib><creatorcontrib>Lee, Jong Min</creatorcontrib><creatorcontrib>Kim, Ji Sun</creatorcontrib><creatorcontrib>Kim, Jaeho</creatorcontrib><creatorcontrib>Kim, Jun Pyo</creatorcontrib><creatorcontrib>Kim, Hee Jin</creatorcontrib><creatorcontrib>Na, Duk L.</creatorcontrib><creatorcontrib>Seo, Sang Won</creatorcontrib><title>Strictly Lobar Microbleeds Reflect Amyloid Angiopathy Regardless of Cerebral and Cerebellar Compartments</title><title>Stroke (1970)</title><addtitle>Stroke</addtitle><description>BACKGROUND AND PURPOSE:We aimed to determine whether lobar cerebellar microbleeds or concomitant lobar cerebellar and deep microbleeds, in the presence of lobar cerebral microbleeds, attribute to underlying advanced cerebral amyloid angiopathy pathology or hypertensive arteriopathy.
METHODS:We categorized 71 patients with suspected cerebral amyloid angiopathy markers (regardless of the presence of deep and cerebellar microbleeds) into 4 groups according to microbleed distributionL (strictly lobar cerebral, n=33), L/LCbll (strictly lobar cerebral and strictly lobar cerebellar microbleeds, n=13), L/Cbll/D (lobar, cerebellar, and deep microbleeds, n=17), and L/D (lobar and deep, n=8). We additionally categorized patients with cerebellar microbleeds into 2 groups according to dentate nucleus involvementstrictly lobar cerebellar (n=16) and dentate (n=14). We then compared clinical characteristics, Aβ (amyloid-β) positivity on PET (positron emission tomography), magnetic resonance imaging cerebral amyloid angiopathy markers, and cerebral small vessel disease burden among groups.
RESULTS:The frequency of Aβ positivity was higher in the L and L/LCbll groups (81.8% and 84.6%) than in the L/Cbll/D and L/D groups (37.5% and 29.4%; P<0.001), while lacune numbers were lower in the L and L/LCbll groups (1.7±3.3 and 1.7±2.6) than in the L/Cbll/D and L/D groups (8.0±10.3 and 13.4±17.7, P=0.001). The L/LCbll group had more lobar cerebral microbleeds than the L group (93.2±121.8 versus 38.0±40.8, P=0.047). The lobar cerebellar group had a higher Aβ positivity (75% versus 28.6%, P=0.011) and lower lacune number (2.3±3.7 versus 8.6±1.2, P=0.041) than the dentate group.
CONCLUSIONS:Strictly lobar cerebral and cerebellar microbleeds are related to cerebral amyloid angiopathy, whereas any combination of concurrent lobar and deep microbleeds suggest hypertensive angiopathy regardless of cerebral or cerebellar compartments.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aniline Compounds</subject><subject>Basal Ganglia Hemorrhage - diagnostic imaging</subject><subject>Benzothiazoles</subject><subject>Cerebellar Diseases - diagnostic imaging</subject><subject>Cerebellar Nuclei - diagnostic imaging</subject><subject>Cerebellum - diagnostic imaging</subject><subject>Cerebral Amyloid Angiopathy - diagnostic imaging</subject><subject>Cerebral Hemorrhage - diagnostic imaging</subject><subject>Cerebral Small Vessel Diseases - diagnostic imaging</subject><subject>Cognitive Dysfunction - diagnostic imaging</subject><subject>Dementia - diagnostic imaging</subject><subject>Female</subject><subject>Humans</subject><subject>Intracranial Hemorrhages - diagnostic imaging</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Positron-Emission Tomography</subject><subject>Radiopharmaceuticals</subject><subject>Stilbenes</subject><subject>Thalamic Diseases - diagnostic imaging</subject><subject>Thiazoles</subject><issn>0039-2499</issn><issn>1524-4628</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1u1DAUhS0EotPCGyCUJZuU65849jIaFYo6qFJb1pHt3HQCzniwParm7fEopUtYWUc-5_j6u4R8oHBJqaSf7x_ubm-uuuuuSH0JTAnVviIr2jBRC8nUa7IC4LpmQuszcp7STwBgXDVvyRnnVKtGwYps73OcXPbHahOsidX3ycVgPeKQqjscPbpcdfPRh2mout3jFPYmb4_l6tHEwWNKVRirNUa00fjK7IZFoPelbB3mvYl5xl1O78ib0fiE75_PC_Ljy9XD-rre3H79tu42tROybWtNW9YyTjmX1NDWohsapAy4MY1SjbPOSmqB84ZxOVrHJKdWCT7wYWyK5Bfk09K7j-H3AVPu5ym50zw7DIfUMyEp14WSLlaxWMuXU4o49vs4zSYeewr9iXH_wrhI3S-MS-zj8wsHO-PwEvoLtRjUYngKPmNMv_zhCWO_RePz9n_d4h_RskBoZQs1AwYFCkB92inlfwCWVJpa</recordid><startdate>20201201</startdate><enddate>20201201</enddate><creator>Jung, Young Hee</creator><creator>Jang, Hyemin</creator><creator>Park, Seong Beom</creator><creator>Choe, Yeong Sim</creator><creator>Park, Yuhyun</creator><creator>Kang, Sung Hoon</creator><creator>Lee, Jong Min</creator><creator>Kim, Ji Sun</creator><creator>Kim, Jaeho</creator><creator>Kim, Jun Pyo</creator><creator>Kim, Hee Jin</creator><creator>Na, Duk L.</creator><creator>Seo, Sang Won</creator><general>American Heart Association, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-8747-0122</orcidid><orcidid>https://orcid.org/0000-0003-3152-1274</orcidid></search><sort><creationdate>20201201</creationdate><title>Strictly Lobar Microbleeds Reflect Amyloid Angiopathy Regardless of Cerebral and Cerebellar Compartments</title><author>Jung, Young Hee ; Jang, Hyemin ; Park, Seong Beom ; Choe, Yeong Sim ; Park, Yuhyun ; Kang, Sung Hoon ; Lee, Jong Min ; Kim, Ji Sun ; Kim, Jaeho ; Kim, Jun Pyo ; Kim, Hee Jin ; Na, Duk L. ; Seo, Sang Won</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4677-917272313361a17becd5e1203aa5885cbcb61b0335236fbc2631b843d3df5bc23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aniline Compounds</topic><topic>Basal Ganglia Hemorrhage - diagnostic imaging</topic><topic>Benzothiazoles</topic><topic>Cerebellar Diseases - diagnostic imaging</topic><topic>Cerebellar Nuclei - diagnostic imaging</topic><topic>Cerebellum - diagnostic imaging</topic><topic>Cerebral Amyloid Angiopathy - diagnostic imaging</topic><topic>Cerebral Hemorrhage - diagnostic imaging</topic><topic>Cerebral Small Vessel Diseases - diagnostic imaging</topic><topic>Cognitive Dysfunction - diagnostic imaging</topic><topic>Dementia - diagnostic imaging</topic><topic>Female</topic><topic>Humans</topic><topic>Intracranial Hemorrhages - diagnostic imaging</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Positron-Emission Tomography</topic><topic>Radiopharmaceuticals</topic><topic>Stilbenes</topic><topic>Thalamic Diseases - diagnostic imaging</topic><topic>Thiazoles</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jung, Young Hee</creatorcontrib><creatorcontrib>Jang, Hyemin</creatorcontrib><creatorcontrib>Park, Seong Beom</creatorcontrib><creatorcontrib>Choe, Yeong Sim</creatorcontrib><creatorcontrib>Park, Yuhyun</creatorcontrib><creatorcontrib>Kang, Sung Hoon</creatorcontrib><creatorcontrib>Lee, Jong Min</creatorcontrib><creatorcontrib>Kim, Ji Sun</creatorcontrib><creatorcontrib>Kim, Jaeho</creatorcontrib><creatorcontrib>Kim, Jun Pyo</creatorcontrib><creatorcontrib>Kim, Hee Jin</creatorcontrib><creatorcontrib>Na, Duk L.</creatorcontrib><creatorcontrib>Seo, Sang Won</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Stroke (1970)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jung, Young Hee</au><au>Jang, Hyemin</au><au>Park, Seong Beom</au><au>Choe, Yeong Sim</au><au>Park, Yuhyun</au><au>Kang, Sung Hoon</au><au>Lee, Jong Min</au><au>Kim, Ji Sun</au><au>Kim, Jaeho</au><au>Kim, Jun Pyo</au><au>Kim, Hee Jin</au><au>Na, Duk L.</au><au>Seo, Sang Won</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Strictly Lobar Microbleeds Reflect Amyloid Angiopathy Regardless of Cerebral and Cerebellar Compartments</atitle><jtitle>Stroke (1970)</jtitle><addtitle>Stroke</addtitle><date>2020-12-01</date><risdate>2020</risdate><volume>51</volume><issue>12</issue><spage>3600</spage><epage>3607</epage><pages>3600-3607</pages><issn>0039-2499</issn><eissn>1524-4628</eissn><abstract>BACKGROUND AND PURPOSE:We aimed to determine whether lobar cerebellar microbleeds or concomitant lobar cerebellar and deep microbleeds, in the presence of lobar cerebral microbleeds, attribute to underlying advanced cerebral amyloid angiopathy pathology or hypertensive arteriopathy.
METHODS:We categorized 71 patients with suspected cerebral amyloid angiopathy markers (regardless of the presence of deep and cerebellar microbleeds) into 4 groups according to microbleed distributionL (strictly lobar cerebral, n=33), L/LCbll (strictly lobar cerebral and strictly lobar cerebellar microbleeds, n=13), L/Cbll/D (lobar, cerebellar, and deep microbleeds, n=17), and L/D (lobar and deep, n=8). We additionally categorized patients with cerebellar microbleeds into 2 groups according to dentate nucleus involvementstrictly lobar cerebellar (n=16) and dentate (n=14). We then compared clinical characteristics, Aβ (amyloid-β) positivity on PET (positron emission tomography), magnetic resonance imaging cerebral amyloid angiopathy markers, and cerebral small vessel disease burden among groups.
RESULTS:The frequency of Aβ positivity was higher in the L and L/LCbll groups (81.8% and 84.6%) than in the L/Cbll/D and L/D groups (37.5% and 29.4%; P<0.001), while lacune numbers were lower in the L and L/LCbll groups (1.7±3.3 and 1.7±2.6) than in the L/Cbll/D and L/D groups (8.0±10.3 and 13.4±17.7, P=0.001). The L/LCbll group had more lobar cerebral microbleeds than the L group (93.2±121.8 versus 38.0±40.8, P=0.047). The lobar cerebellar group had a higher Aβ positivity (75% versus 28.6%, P=0.011) and lower lacune number (2.3±3.7 versus 8.6±1.2, P=0.041) than the dentate group.
CONCLUSIONS:Strictly lobar cerebral and cerebellar microbleeds are related to cerebral amyloid angiopathy, whereas any combination of concurrent lobar and deep microbleeds suggest hypertensive angiopathy regardless of cerebral or cerebellar compartments.</abstract><cop>United States</cop><pub>American Heart Association, Inc</pub><pmid>33198580</pmid><doi>10.1161/STROKEAHA.119.028487</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-8747-0122</orcidid><orcidid>https://orcid.org/0000-0003-3152-1274</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0039-2499 |
| ispartof | Stroke (1970), 2020-12, Vol.51 (12), p.3600-3607 |
| issn | 0039-2499 1524-4628 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2461391529 |
| source | Journals@Ovid Ovid Autoload; MEDLINE; American Heart Association Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Aged Aged, 80 and over Aniline Compounds Basal Ganglia Hemorrhage - diagnostic imaging Benzothiazoles Cerebellar Diseases - diagnostic imaging Cerebellar Nuclei - diagnostic imaging Cerebellum - diagnostic imaging Cerebral Amyloid Angiopathy - diagnostic imaging Cerebral Hemorrhage - diagnostic imaging Cerebral Small Vessel Diseases - diagnostic imaging Cognitive Dysfunction - diagnostic imaging Dementia - diagnostic imaging Female Humans Intracranial Hemorrhages - diagnostic imaging Magnetic Resonance Imaging Male Positron-Emission Tomography Radiopharmaceuticals Stilbenes Thalamic Diseases - diagnostic imaging Thiazoles |
| title | Strictly Lobar Microbleeds Reflect Amyloid Angiopathy Regardless of Cerebral and Cerebellar Compartments |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T10%3A16%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Strictly%20Lobar%20Microbleeds%20Reflect%20Amyloid%20Angiopathy%20Regardless%20of%20Cerebral%20and%20Cerebellar%20Compartments&rft.jtitle=Stroke%20(1970)&rft.au=Jung,%20Young%20Hee&rft.date=2020-12-01&rft.volume=51&rft.issue=12&rft.spage=3600&rft.epage=3607&rft.pages=3600-3607&rft.issn=0039-2499&rft.eissn=1524-4628&rft_id=info:doi/10.1161/STROKEAHA.119.028487&rft_dat=%3Cproquest_cross%3E2461391529%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2461391529&rft_id=info:pmid/33198580&rfr_iscdi=true |