The Skinner Burial of Ontario, Canada, and the Question of Paget’s Disease in the Americas
To examine a possible case of Paget’s disease of bone (PDB) in an Indigenous pre-contact male from Canada, individual D of the Skinner site in Ontario. Radiographs, CT scan and histological analysis. The histological analysis revealed the mosaic pattern that characterizes PDB. CT scans show advanced...
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| Veröffentlicht in: | International journal of paleopathology 2021-03, Vol.32, p.9-16 |
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| creator | Spence, Michael W. Fox, William A. Gardner, Janet Beauchesne, Patrick |
| description | To examine a possible case of Paget’s disease of bone (PDB) in an Indigenous pre-contact male from Canada, individual D of the Skinner site in Ontario.
Radiographs, CT scan and histological analysis.
The histological analysis revealed the mosaic pattern that characterizes PDB. CT scans show advanced sclerosis of the cranium and a diminished diplӧe with osteolytic lesions.
The pathological features that have been identified are collectively characteristic of PDB.
The Skinner case advances our understanding of the global history and distribution of PDB.
Only two New World cases have been identified and neither has been studied in sufficient detail.
The older individuals in precolonial New World skeletal series should be given CT scans, which are non-intrusive, to be followed by histological and genetic analyses when indicated. |
| doi_str_mv | 10.1016/j.ijpp.2020.10.007 |
| format | Article |
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Radiographs, CT scan and histological analysis.
The histological analysis revealed the mosaic pattern that characterizes PDB. CT scans show advanced sclerosis of the cranium and a diminished diplӧe with osteolytic lesions.
The pathological features that have been identified are collectively characteristic of PDB.
The Skinner case advances our understanding of the global history and distribution of PDB.
Only two New World cases have been identified and neither has been studied in sufficient detail.
The older individuals in precolonial New World skeletal series should be given CT scans, which are non-intrusive, to be followed by histological and genetic analyses when indicated.</description><identifier>ISSN: 1879-9817</identifier><identifier>EISSN: 1879-9825</identifier><identifier>DOI: 10.1016/j.ijpp.2020.10.007</identifier><identifier>PMID: 33197696</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Burial ; Canada ; History, Ancient ; Humans ; Late Woodland ; Male ; metabolic bone disorder ; Ontario ; Osteitis Deformans - diagnostic imaging ; Osteitis Deformans - history ; osteosclerosis ; Paleopathology ; Radiography ; Skull</subject><ispartof>International journal of paleopathology, 2021-03, Vol.32, p.9-16</ispartof><rights>2020 Elsevier Inc.</rights><rights>Copyright © 2020 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-795441e7ff692621a8731e7266e45b14ab8e176c20666781f2d663ca3f2b79063</citedby><cites>FETCH-LOGICAL-c356t-795441e7ff692621a8731e7266e45b14ab8e176c20666781f2d663ca3f2b79063</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.ijpp.2020.10.007$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33197696$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Spence, Michael W.</creatorcontrib><creatorcontrib>Fox, William A.</creatorcontrib><creatorcontrib>Gardner, Janet</creatorcontrib><creatorcontrib>Beauchesne, Patrick</creatorcontrib><title>The Skinner Burial of Ontario, Canada, and the Question of Paget’s Disease in the Americas</title><title>International journal of paleopathology</title><addtitle>Int J Paleopathol</addtitle><description>To examine a possible case of Paget’s disease of bone (PDB) in an Indigenous pre-contact male from Canada, individual D of the Skinner site in Ontario.
Radiographs, CT scan and histological analysis.
The histological analysis revealed the mosaic pattern that characterizes PDB. CT scans show advanced sclerosis of the cranium and a diminished diplӧe with osteolytic lesions.
The pathological features that have been identified are collectively characteristic of PDB.
The Skinner case advances our understanding of the global history and distribution of PDB.
Only two New World cases have been identified and neither has been studied in sufficient detail.
The older individuals in precolonial New World skeletal series should be given CT scans, which are non-intrusive, to be followed by histological and genetic analyses when indicated.</description><subject>Burial</subject><subject>Canada</subject><subject>History, Ancient</subject><subject>Humans</subject><subject>Late Woodland</subject><subject>Male</subject><subject>metabolic bone disorder</subject><subject>Ontario</subject><subject>Osteitis Deformans - diagnostic imaging</subject><subject>Osteitis Deformans - history</subject><subject>osteosclerosis</subject><subject>Paleopathology</subject><subject>Radiography</subject><subject>Skull</subject><issn>1879-9817</issn><issn>1879-9825</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtOwzAQhi0Eogh6ARbISxa0-JGME4kNlKeEVBBlh2Q5zgRcWqfYKRI7rsH1OAkJBZZ4M_bom1-ej5BdzoaccTicDt10sRgKJrrGkDG1RrZ4pvJBnol0_e_OVY_0Y5yy9gCTLMk2SU9KnivIYYs8TJ6Q3j077zHQk2VwZkbrio59Y4KrD-jIeFOaA2p8SZsWvV1ibFztO-jGPGLz-f4R6amLaCJS57-h4zkGZ03cIRuVmUXs_9Rtcn9-NhldDq7HF1ej4-uBlSk0A5WnScJRVRXkAgQ3mZLtUwBgkhY8MUWGXIEVDABUxitRAkhrZCUKlTOQ22R_lbsI9Uv3QT130eJsZjzWy6hFAlzmjAveomKF2lDHGLDSi-DmJrxpznQnVk91J1Z3YrteK7Yd2vvJXxZzLP9GfjW2wNEKwHbLV4dBR-vQWyxdQNvosnb_5X8BosWHoQ</recordid><startdate>202103</startdate><enddate>202103</enddate><creator>Spence, Michael W.</creator><creator>Fox, William A.</creator><creator>Gardner, Janet</creator><creator>Beauchesne, Patrick</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202103</creationdate><title>The Skinner Burial of Ontario, Canada, and the Question of Paget’s Disease in the Americas</title><author>Spence, Michael W. ; Fox, William A. ; Gardner, Janet ; Beauchesne, Patrick</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-795441e7ff692621a8731e7266e45b14ab8e176c20666781f2d663ca3f2b79063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Burial</topic><topic>Canada</topic><topic>History, Ancient</topic><topic>Humans</topic><topic>Late Woodland</topic><topic>Male</topic><topic>metabolic bone disorder</topic><topic>Ontario</topic><topic>Osteitis Deformans - diagnostic imaging</topic><topic>Osteitis Deformans - history</topic><topic>osteosclerosis</topic><topic>Paleopathology</topic><topic>Radiography</topic><topic>Skull</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Spence, Michael W.</creatorcontrib><creatorcontrib>Fox, William A.</creatorcontrib><creatorcontrib>Gardner, Janet</creatorcontrib><creatorcontrib>Beauchesne, Patrick</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of paleopathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Spence, Michael W.</au><au>Fox, William A.</au><au>Gardner, Janet</au><au>Beauchesne, Patrick</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Skinner Burial of Ontario, Canada, and the Question of Paget’s Disease in the Americas</atitle><jtitle>International journal of paleopathology</jtitle><addtitle>Int J Paleopathol</addtitle><date>2021-03</date><risdate>2021</risdate><volume>32</volume><spage>9</spage><epage>16</epage><pages>9-16</pages><issn>1879-9817</issn><eissn>1879-9825</eissn><abstract>To examine a possible case of Paget’s disease of bone (PDB) in an Indigenous pre-contact male from Canada, individual D of the Skinner site in Ontario.
Radiographs, CT scan and histological analysis.
The histological analysis revealed the mosaic pattern that characterizes PDB. CT scans show advanced sclerosis of the cranium and a diminished diplӧe with osteolytic lesions.
The pathological features that have been identified are collectively characteristic of PDB.
The Skinner case advances our understanding of the global history and distribution of PDB.
Only two New World cases have been identified and neither has been studied in sufficient detail.
The older individuals in precolonial New World skeletal series should be given CT scans, which are non-intrusive, to be followed by histological and genetic analyses when indicated.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>33197696</pmid><doi>10.1016/j.ijpp.2020.10.007</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1879-9817 |
| ispartof | International journal of paleopathology, 2021-03, Vol.32, p.9-16 |
| issn | 1879-9817 1879-9825 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Burial Canada History, Ancient Humans Late Woodland Male metabolic bone disorder Ontario Osteitis Deformans - diagnostic imaging Osteitis Deformans - history osteosclerosis Paleopathology Radiography Skull |
| title | The Skinner Burial of Ontario, Canada, and the Question of Paget’s Disease in the Americas |
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