The effects of perinatal fluoxetine exposure on emotionality behaviours and cortical and hippocampal glutamatergic receptors in female Sprague-Dawley and Wistar-Kyoto rats

There is increasing concern regarding the use of selective serotonin reuptake inhibitors (SSRIs) in pregnancy. Animal studies repeatedly show increased anxiety- and depressive-like behaviours in offspring exposed perinatally to SSRIs, however much of this research is in male offspring. The primary a...

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Veröffentlicht in:	Progress in neuro-psychopharmacology & biological psychiatry 2021-06, Vol.108, p.110174-110174, Article 110174
Hauptverfasser:	Millard, Samuel J., Lum, Jeremy S., Fernandez, Francesca, Weston-Green, Katrina, Newell, Kelly A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Antidepressant Anxiety - drug therapy Depressive Disorder - drug therapy Disease Models, Animal Elevated Plus Maze Test Female Glutamate Hippocampus - chemistry Hippocampus - drug effects Offspring Perinatal Perinatal depression Prefrontal Cortex - chemistry Prefrontal Cortex - drug effects Pregnant Pyrimidines - pharmacology Rats Rats, Inbred WKY Rats, Sprague-Dawley Receptors, Glutamate - analysis Receptors, Glutamate - drug effects SSRI Wistar-Kyoto
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