Short-Term Tea Consumption Is Not Associated with a Reduction in Blood Lipids or Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
A recent systematic review of epidemiological evidence suggests that higher amounts of tea intake are associated with lower risks of cardiovascular disease (CVD) incidence and mortality. Our study objective was to assess mechanisms by which tea consumption may influence CVD risks. A systematic revie...
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| Veröffentlicht in: | The Journal of nutrition 2020-12, Vol.150 (12), p.3269-3279 |
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| creator | Igho-Osagie, Ebuwa Cara, Kelly Wang, Deena Yao, Qisi Penkert, Laura P Cassidy, Aedin Ferruzzi, Mario Jacques, Paul F Johnson, Elizabeth J Chung, Mei Wallace, Taylor |
| description | A recent systematic review of epidemiological evidence suggests that higher amounts of tea intake are associated with lower risks of cardiovascular disease (CVD) incidence and mortality.
Our study objective was to assess mechanisms by which tea consumption may influence CVD risks.
A systematic review and meta-analysis was conducted to investigate the effects of green and/or black tea consumption (≥4 wk) on systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride (TG) in healthy populations and among at-risk adults (analyzed separately) with metabolic syndrome, prediabetes, and hypercholesterolemia. The Grading of Recommendations Assessment, Development and Evaluation approach was used to rate the strength of evidence (SoE).
A total of 14 unique RCTs which randomly assigned 798 participants to either green tea, black tea, or placebo controls were included in our analyses. Intervention durations ranged from 4 to 24 wk (mean: 7.4 wk). Individual studies were judged as moderate to high quality based on risk of bias assessments. SoE was low to moderate owing to low sample sizes and insufficient power for most included studies to observe changes in the measured CVD biomarkers. Meta-analyses showed no significant effects of tea consumption on SBP, DBP, total cholesterol, LDL cholesterol, HDL cholesterol, and TG in healthy and at-risk adults (i.e., adults with obesity, prediabetes, borderline hypercholesterolemia, and metabolic syndrome).
Short-term (4–24 wk) tea consumption does not appear to significantly affect blood pressure or lipids in healthy or at-risk adults, although the evidence is limited by insufficient power to detect changes in these CVD biomarkers. High-quality RCTs with longer durations and sufficient sample sizes are needed to fully elucidate the effects of tea. This systematic review was registered atwww.crd.york.ac.uk/prospero/as CRD42020134513. |
| doi_str_mv | 10.1093/jn/nxaa295 |
| format | Article |
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Our study objective was to assess mechanisms by which tea consumption may influence CVD risks.
A systematic review and meta-analysis was conducted to investigate the effects of green and/or black tea consumption (≥4 wk) on systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride (TG) in healthy populations and among at-risk adults (analyzed separately) with metabolic syndrome, prediabetes, and hypercholesterolemia. The Grading of Recommendations Assessment, Development and Evaluation approach was used to rate the strength of evidence (SoE).
A total of 14 unique RCTs which randomly assigned 798 participants to either green tea, black tea, or placebo controls were included in our analyses. Intervention durations ranged from 4 to 24 wk (mean: 7.4 wk). Individual studies were judged as moderate to high quality based on risk of bias assessments. SoE was low to moderate owing to low sample sizes and insufficient power for most included studies to observe changes in the measured CVD biomarkers. Meta-analyses showed no significant effects of tea consumption on SBP, DBP, total cholesterol, LDL cholesterol, HDL cholesterol, and TG in healthy and at-risk adults (i.e., adults with obesity, prediabetes, borderline hypercholesterolemia, and metabolic syndrome).
Short-term (4–24 wk) tea consumption does not appear to significantly affect blood pressure or lipids in healthy or at-risk adults, although the evidence is limited by insufficient power to detect changes in these CVD biomarkers. High-quality RCTs with longer durations and sufficient sample sizes are needed to fully elucidate the effects of tea. This systematic review was registered atwww.crd.york.ac.uk/prospero/as CRD42020134513.</description><identifier>ISSN: 0022-3166</identifier><identifier>EISSN: 1541-6100</identifier><identifier>DOI: 10.1093/jn/nxaa295</identifier><identifier>PMID: 33188386</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adults ; Biomarkers ; Black tea ; Blood pressure ; Blood Pressure - drug effects ; Camellia sinensis ; Cardiovascular disease ; Cardiovascular diseases ; Change detection ; Cholesterol ; Consumption ; Drug Administration Schedule ; Epidemiology ; Green tea ; Health risks ; Heart diseases ; High density lipoprotein ; Humans ; Hypercholesterolemia ; Lipids ; Lipids - blood ; Low density lipoprotein ; Meta-analysis ; Metabolic disorders ; Metabolic syndrome ; Mortality ; Reviews ; Risk analysis ; Tea ; Triglycerides</subject><ispartof>The Journal of nutrition, 2020-12, Vol.150 (12), p.3269-3279</ispartof><rights>2020 American Society for Nutrition.</rights><rights>The Author(s) 2020. Published by Oxford University Press on behalf of the American Society for Nutrition. 2020</rights><rights>The Author(s) 2020. Published by Oxford University Press on behalf of the American Society for Nutrition.</rights><rights>Copyright American Institute of Nutrition Dec 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c426t-afa5691932f2a297d0f770141d0938bfba879a32ec92e1263ac608dc83ca0d9e3</citedby><cites>FETCH-LOGICAL-c426t-afa5691932f2a297d0f770141d0938bfba879a32ec92e1263ac608dc83ca0d9e3</cites><orcidid>0000-0002-5583-2870 ; 0000-0002-9403-2745 ; 0000-0003-0048-5602</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33188386$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Igho-Osagie, Ebuwa</creatorcontrib><creatorcontrib>Cara, Kelly</creatorcontrib><creatorcontrib>Wang, Deena</creatorcontrib><creatorcontrib>Yao, Qisi</creatorcontrib><creatorcontrib>Penkert, Laura P</creatorcontrib><creatorcontrib>Cassidy, Aedin</creatorcontrib><creatorcontrib>Ferruzzi, Mario</creatorcontrib><creatorcontrib>Jacques, Paul F</creatorcontrib><creatorcontrib>Johnson, Elizabeth J</creatorcontrib><creatorcontrib>Chung, Mei</creatorcontrib><creatorcontrib>Wallace, Taylor</creatorcontrib><title>Short-Term Tea Consumption Is Not Associated with a Reduction in Blood Lipids or Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials</title><title>The Journal of nutrition</title><addtitle>J Nutr</addtitle><description>A recent systematic review of epidemiological evidence suggests that higher amounts of tea intake are associated with lower risks of cardiovascular disease (CVD) incidence and mortality.
Our study objective was to assess mechanisms by which tea consumption may influence CVD risks.
A systematic review and meta-analysis was conducted to investigate the effects of green and/or black tea consumption (≥4 wk) on systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride (TG) in healthy populations and among at-risk adults (analyzed separately) with metabolic syndrome, prediabetes, and hypercholesterolemia. The Grading of Recommendations Assessment, Development and Evaluation approach was used to rate the strength of evidence (SoE).
A total of 14 unique RCTs which randomly assigned 798 participants to either green tea, black tea, or placebo controls were included in our analyses. Intervention durations ranged from 4 to 24 wk (mean: 7.4 wk). Individual studies were judged as moderate to high quality based on risk of bias assessments. SoE was low to moderate owing to low sample sizes and insufficient power for most included studies to observe changes in the measured CVD biomarkers. Meta-analyses showed no significant effects of tea consumption on SBP, DBP, total cholesterol, LDL cholesterol, HDL cholesterol, and TG in healthy and at-risk adults (i.e., adults with obesity, prediabetes, borderline hypercholesterolemia, and metabolic syndrome).
Short-term (4–24 wk) tea consumption does not appear to significantly affect blood pressure or lipids in healthy or at-risk adults, although the evidence is limited by insufficient power to detect changes in these CVD biomarkers. High-quality RCTs with longer durations and sufficient sample sizes are needed to fully elucidate the effects of tea. This systematic review was registered atwww.crd.york.ac.uk/prospero/as CRD42020134513.</description><subject>Adults</subject><subject>Biomarkers</subject><subject>Black tea</subject><subject>Blood pressure</subject><subject>Blood Pressure - drug effects</subject><subject>Camellia sinensis</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular diseases</subject><subject>Change detection</subject><subject>Cholesterol</subject><subject>Consumption</subject><subject>Drug Administration Schedule</subject><subject>Epidemiology</subject><subject>Green tea</subject><subject>Health risks</subject><subject>Heart diseases</subject><subject>High density lipoprotein</subject><subject>Humans</subject><subject>Hypercholesterolemia</subject><subject>Lipids</subject><subject>Lipids - blood</subject><subject>Low density lipoprotein</subject><subject>Meta-analysis</subject><subject>Metabolic disorders</subject><subject>Metabolic syndrome</subject><subject>Mortality</subject><subject>Reviews</subject><subject>Risk analysis</subject><subject>Tea</subject><subject>Triglycerides</subject><issn>0022-3166</issn><issn>1541-6100</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kcuKFDEUhoMoTju68QEkIIII5eRSlapy1zZeBtoLM-26SCenmDRVSU1OyrF9Gh_VjN26EHF1Qvj-c_l_Qh5z9pKzVp7t_Jn_prVoqztkwauSF4ozdpcsGBOikFypE_IAcccY42Xb3CcnUvKmkY1akB-XVyGmYgNxpBvQdBU8zuOUXPD0HOnHkOgSMRinE1h649IV1fQC7Gx-Ic7T10MIlq7d5CzSEOnnCIhzhFd0SS_3mGDUyZms-erghmpv6QdIulh6PezRZUlPL_JvGN33PCHPTzEMQ35uotMDPiT3-lzg0bGeki9v32xW74v1p3fnq-W6MKVQqdC9rlTLWyl6kZ2oLevrOp_LbXao2fZb3dStlgJMK4ALJbVRrLGmkUYz24I8Jc8PfacYrmfA1I0ODQyD9hBm7ESpWK3KirOMPv0L3YU55ntuqZqpvEfFM_XiQJkYECP03RTdqOO-46y7za3b-e6YW4afHFvO2xHsH_R3UBl4dgDCPP2_UXngIHuVHY8dGgfegHURTOpscP-S_QTJFrQ5</recordid><startdate>20201201</startdate><enddate>20201201</enddate><creator>Igho-Osagie, Ebuwa</creator><creator>Cara, Kelly</creator><creator>Wang, Deena</creator><creator>Yao, Qisi</creator><creator>Penkert, Laura P</creator><creator>Cassidy, Aedin</creator><creator>Ferruzzi, Mario</creator><creator>Jacques, Paul F</creator><creator>Johnson, Elizabeth J</creator><creator>Chung, Mei</creator><creator>Wallace, Taylor</creator><general>Elsevier Inc</general><general>Oxford University Press</general><general>American Institute of Nutrition</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-5583-2870</orcidid><orcidid>https://orcid.org/0000-0002-9403-2745</orcidid><orcidid>https://orcid.org/0000-0003-0048-5602</orcidid></search><sort><creationdate>20201201</creationdate><title>Short-Term Tea Consumption Is Not Associated with a Reduction in Blood Lipids or Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials</title><author>Igho-Osagie, Ebuwa ; 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Our study objective was to assess mechanisms by which tea consumption may influence CVD risks.
A systematic review and meta-analysis was conducted to investigate the effects of green and/or black tea consumption (≥4 wk) on systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride (TG) in healthy populations and among at-risk adults (analyzed separately) with metabolic syndrome, prediabetes, and hypercholesterolemia. The Grading of Recommendations Assessment, Development and Evaluation approach was used to rate the strength of evidence (SoE).
A total of 14 unique RCTs which randomly assigned 798 participants to either green tea, black tea, or placebo controls were included in our analyses. Intervention durations ranged from 4 to 24 wk (mean: 7.4 wk). Individual studies were judged as moderate to high quality based on risk of bias assessments. SoE was low to moderate owing to low sample sizes and insufficient power for most included studies to observe changes in the measured CVD biomarkers. Meta-analyses showed no significant effects of tea consumption on SBP, DBP, total cholesterol, LDL cholesterol, HDL cholesterol, and TG in healthy and at-risk adults (i.e., adults with obesity, prediabetes, borderline hypercholesterolemia, and metabolic syndrome).
Short-term (4–24 wk) tea consumption does not appear to significantly affect blood pressure or lipids in healthy or at-risk adults, although the evidence is limited by insufficient power to detect changes in these CVD biomarkers. High-quality RCTs with longer durations and sufficient sample sizes are needed to fully elucidate the effects of tea. This systematic review was registered atwww.crd.york.ac.uk/prospero/as CRD42020134513.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>33188386</pmid><doi>10.1093/jn/nxaa295</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0002-5583-2870</orcidid><orcidid>https://orcid.org/0000-0002-9403-2745</orcidid><orcidid>https://orcid.org/0000-0003-0048-5602</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Adults Biomarkers Black tea Blood pressure Blood Pressure - drug effects Camellia sinensis Cardiovascular disease Cardiovascular diseases Change detection Cholesterol Consumption Drug Administration Schedule Epidemiology Green tea Health risks Heart diseases High density lipoprotein Humans Hypercholesterolemia Lipids Lipids - blood Low density lipoprotein Meta-analysis Metabolic disorders Metabolic syndrome Mortality Reviews Risk analysis Tea Triglycerides |
| title | Short-Term Tea Consumption Is Not Associated with a Reduction in Blood Lipids or Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials |
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