Assessment of delayed diagnosis and treatment in multiple sclerosis patients during 1990–2016
Multiple sclerosis (MS) is the most common inflammatory demyelinating disease in the central nervous system. It is one of the major causes of disability in young adults. Early diagnosis and treatment of this disease could decrease later disability and additional costs. In this cross-sectional analyt...
Gespeichert in:
Veröffentlicht in: | Acta neurologica Belgica 2021-02, Vol.121 (1), p.199-204 |
---|---|
Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 204 |
---|---|
container_issue | 1 |
container_start_page | 199 |
container_title | Acta neurologica Belgica |
container_volume | 121 |
creator | Ghiasian, Masoud Faryadras, Mohammad Mansour, Maryam Khanlarzadeh, Elham Mazaheri, Shahir |
description | Multiple sclerosis (MS) is the most common inflammatory demyelinating disease in the central nervous system. It is one of the major causes of disability in young adults. Early diagnosis and treatment of this disease could decrease later disability and additional costs. In this cross-sectional analytical study, a total of 351 patients were selected from among the multiple sclerosis patients that went to MS clinic or neurologic clinic in 1990–2016. Data were collected and analysed by SPSS v16. This study was conducted on 82.6% females and 17.4% males. Family history of MS was positive in 12.8% of cases. Mean time of onset of symptoms till first medical visit was 3.25 months. Mean time from first medical visit to diagnosis was 14.98 months. Mean time from onset of symptoms till diagnosis was 18.01 months and the mean time from onset of symptoms till initiation of treatment was 18.73 months. Also, 29.3% of cases had delay in first medical visit and 42.2% of cases had delay in diagnosis of MS more than 6 weeks from first medical visit. Overall, delay in first medical visit and diagnosis of MS has decreased over the years. However, there is still delay in diagnosis of MS. Factors associated with delay are low education, male gender, living in rural areas, primary progressive MS, age at MS diagnosis and first clinical symptoms. |
doi_str_mv | 10.1007/s13760-020-01528-7 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2460081032</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2460081032</sourcerecordid><originalsourceid>FETCH-LOGICAL-c347t-20d670918fa74fd6d759378c4ae371d1d10d6d851bc9074edf2abd3db9bfe5253</originalsourceid><addsrcrecordid>eNp9kDtOxDAQhi0EgtXCBSiQS5rA2E7iuFwhXhISDdSWE09QUF54kmI77sANOQneB5R4ZLmYb36NP8bOBVwJAH1NQukcEpDxikwWiT5gCylTSKQx6pAtQAEkBsCcsDOid4gnzaXQ-TE7UUoUoIRaMLsiQqIO-4kPNffYujV67hv31g_UEHe951NAN22Rpufd3E7N2CKnqsWwZUY3NbFL3M-h6d-4MAa-P78kiPyUHdWuJTzbv0v2enf7cvOQPD3fP96snpJKpXpKJPhcgxFF7XRa-9zrzChdVKlDpYWPFQFfZKKsDOgUfS1d6ZUvTVljJjO1ZJe73DEMHzPSZLuGKmxb1-Mwk5VpDlAIUDKicodWcXsKWNsxNJ0LayvAbtzanVsb3dqtW6vj0MU-fy479H8jvyYjoHYAjRsHGOz7MIc-_vm_2B9kAoTr</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2460081032</pqid></control><display><type>article</type><title>Assessment of delayed diagnosis and treatment in multiple sclerosis patients during 1990–2016</title><source>Springer Nature - Complete Springer Journals</source><creator>Ghiasian, Masoud ; Faryadras, Mohammad ; Mansour, Maryam ; Khanlarzadeh, Elham ; Mazaheri, Shahir</creator><creatorcontrib>Ghiasian, Masoud ; Faryadras, Mohammad ; Mansour, Maryam ; Khanlarzadeh, Elham ; Mazaheri, Shahir</creatorcontrib><description>Multiple sclerosis (MS) is the most common inflammatory demyelinating disease in the central nervous system. It is one of the major causes of disability in young adults. Early diagnosis and treatment of this disease could decrease later disability and additional costs. In this cross-sectional analytical study, a total of 351 patients were selected from among the multiple sclerosis patients that went to MS clinic or neurologic clinic in 1990–2016. Data were collected and analysed by SPSS v16. This study was conducted on 82.6% females and 17.4% males. Family history of MS was positive in 12.8% of cases. Mean time of onset of symptoms till first medical visit was 3.25 months. Mean time from first medical visit to diagnosis was 14.98 months. Mean time from onset of symptoms till diagnosis was 18.01 months and the mean time from onset of symptoms till initiation of treatment was 18.73 months. Also, 29.3% of cases had delay in first medical visit and 42.2% of cases had delay in diagnosis of MS more than 6 weeks from first medical visit. Overall, delay in first medical visit and diagnosis of MS has decreased over the years. However, there is still delay in diagnosis of MS. Factors associated with delay are low education, male gender, living in rural areas, primary progressive MS, age at MS diagnosis and first clinical symptoms.</description><identifier>ISSN: 0300-9009</identifier><identifier>EISSN: 2240-2993</identifier><identifier>DOI: 10.1007/s13760-020-01528-7</identifier><identifier>PMID: 33180313</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Biomedical and Life Sciences ; Biomedicine ; Medicine/Public Health ; Neurology ; Neuroradiology ; Neurosciences ; Original Article</subject><ispartof>Acta neurologica Belgica, 2021-02, Vol.121 (1), p.199-204</ispartof><rights>Belgian Neurological Society 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c347t-20d670918fa74fd6d759378c4ae371d1d10d6d851bc9074edf2abd3db9bfe5253</citedby><cites>FETCH-LOGICAL-c347t-20d670918fa74fd6d759378c4ae371d1d10d6d851bc9074edf2abd3db9bfe5253</cites><orcidid>0000-0002-4490-6897 ; 0000-0001-6812-8922</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s13760-020-01528-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s13760-020-01528-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51298</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33180313$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ghiasian, Masoud</creatorcontrib><creatorcontrib>Faryadras, Mohammad</creatorcontrib><creatorcontrib>Mansour, Maryam</creatorcontrib><creatorcontrib>Khanlarzadeh, Elham</creatorcontrib><creatorcontrib>Mazaheri, Shahir</creatorcontrib><title>Assessment of delayed diagnosis and treatment in multiple sclerosis patients during 1990–2016</title><title>Acta neurologica Belgica</title><addtitle>Acta Neurol Belg</addtitle><addtitle>Acta Neurol Belg</addtitle><description>Multiple sclerosis (MS) is the most common inflammatory demyelinating disease in the central nervous system. It is one of the major causes of disability in young adults. Early diagnosis and treatment of this disease could decrease later disability and additional costs. In this cross-sectional analytical study, a total of 351 patients were selected from among the multiple sclerosis patients that went to MS clinic or neurologic clinic in 1990–2016. Data were collected and analysed by SPSS v16. This study was conducted on 82.6% females and 17.4% males. Family history of MS was positive in 12.8% of cases. Mean time of onset of symptoms till first medical visit was 3.25 months. Mean time from first medical visit to diagnosis was 14.98 months. Mean time from onset of symptoms till diagnosis was 18.01 months and the mean time from onset of symptoms till initiation of treatment was 18.73 months. Also, 29.3% of cases had delay in first medical visit and 42.2% of cases had delay in diagnosis of MS more than 6 weeks from first medical visit. Overall, delay in first medical visit and diagnosis of MS has decreased over the years. However, there is still delay in diagnosis of MS. Factors associated with delay are low education, male gender, living in rural areas, primary progressive MS, age at MS diagnosis and first clinical symptoms.</description><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Medicine/Public Health</subject><subject>Neurology</subject><subject>Neuroradiology</subject><subject>Neurosciences</subject><subject>Original Article</subject><issn>0300-9009</issn><issn>2240-2993</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kDtOxDAQhi0EgtXCBSiQS5rA2E7iuFwhXhISDdSWE09QUF54kmI77sANOQneB5R4ZLmYb36NP8bOBVwJAH1NQukcEpDxikwWiT5gCylTSKQx6pAtQAEkBsCcsDOid4gnzaXQ-TE7UUoUoIRaMLsiQqIO-4kPNffYujV67hv31g_UEHe951NAN22Rpufd3E7N2CKnqsWwZUY3NbFL3M-h6d-4MAa-P78kiPyUHdWuJTzbv0v2enf7cvOQPD3fP96snpJKpXpKJPhcgxFF7XRa-9zrzChdVKlDpYWPFQFfZKKsDOgUfS1d6ZUvTVljJjO1ZJe73DEMHzPSZLuGKmxb1-Mwk5VpDlAIUDKicodWcXsKWNsxNJ0LayvAbtzanVsb3dqtW6vj0MU-fy479H8jvyYjoHYAjRsHGOz7MIc-_vm_2B9kAoTr</recordid><startdate>20210201</startdate><enddate>20210201</enddate><creator>Ghiasian, Masoud</creator><creator>Faryadras, Mohammad</creator><creator>Mansour, Maryam</creator><creator>Khanlarzadeh, Elham</creator><creator>Mazaheri, Shahir</creator><general>Springer International Publishing</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-4490-6897</orcidid><orcidid>https://orcid.org/0000-0001-6812-8922</orcidid></search><sort><creationdate>20210201</creationdate><title>Assessment of delayed diagnosis and treatment in multiple sclerosis patients during 1990–2016</title><author>Ghiasian, Masoud ; Faryadras, Mohammad ; Mansour, Maryam ; Khanlarzadeh, Elham ; Mazaheri, Shahir</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c347t-20d670918fa74fd6d759378c4ae371d1d10d6d851bc9074edf2abd3db9bfe5253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Medicine/Public Health</topic><topic>Neurology</topic><topic>Neuroradiology</topic><topic>Neurosciences</topic><topic>Original Article</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ghiasian, Masoud</creatorcontrib><creatorcontrib>Faryadras, Mohammad</creatorcontrib><creatorcontrib>Mansour, Maryam</creatorcontrib><creatorcontrib>Khanlarzadeh, Elham</creatorcontrib><creatorcontrib>Mazaheri, Shahir</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta neurologica Belgica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ghiasian, Masoud</au><au>Faryadras, Mohammad</au><au>Mansour, Maryam</au><au>Khanlarzadeh, Elham</au><au>Mazaheri, Shahir</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of delayed diagnosis and treatment in multiple sclerosis patients during 1990–2016</atitle><jtitle>Acta neurologica Belgica</jtitle><stitle>Acta Neurol Belg</stitle><addtitle>Acta Neurol Belg</addtitle><date>2021-02-01</date><risdate>2021</risdate><volume>121</volume><issue>1</issue><spage>199</spage><epage>204</epage><pages>199-204</pages><issn>0300-9009</issn><eissn>2240-2993</eissn><abstract>Multiple sclerosis (MS) is the most common inflammatory demyelinating disease in the central nervous system. It is one of the major causes of disability in young adults. Early diagnosis and treatment of this disease could decrease later disability and additional costs. In this cross-sectional analytical study, a total of 351 patients were selected from among the multiple sclerosis patients that went to MS clinic or neurologic clinic in 1990–2016. Data were collected and analysed by SPSS v16. This study was conducted on 82.6% females and 17.4% males. Family history of MS was positive in 12.8% of cases. Mean time of onset of symptoms till first medical visit was 3.25 months. Mean time from first medical visit to diagnosis was 14.98 months. Mean time from onset of symptoms till diagnosis was 18.01 months and the mean time from onset of symptoms till initiation of treatment was 18.73 months. Also, 29.3% of cases had delay in first medical visit and 42.2% of cases had delay in diagnosis of MS more than 6 weeks from first medical visit. Overall, delay in first medical visit and diagnosis of MS has decreased over the years. However, there is still delay in diagnosis of MS. Factors associated with delay are low education, male gender, living in rural areas, primary progressive MS, age at MS diagnosis and first clinical symptoms.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>33180313</pmid><doi>10.1007/s13760-020-01528-7</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-4490-6897</orcidid><orcidid>https://orcid.org/0000-0001-6812-8922</orcidid></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0300-9009 |
ispartof | Acta neurologica Belgica, 2021-02, Vol.121 (1), p.199-204 |
issn | 0300-9009 2240-2993 |
language | eng |
recordid | cdi_proquest_miscellaneous_2460081032 |
source | Springer Nature - Complete Springer Journals |
subjects | Biomedical and Life Sciences Biomedicine Medicine/Public Health Neurology Neuroradiology Neurosciences Original Article |
title | Assessment of delayed diagnosis and treatment in multiple sclerosis patients during 1990–2016 |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T02%3A30%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Assessment%20of%20delayed%20diagnosis%20and%20treatment%20in%20multiple%20sclerosis%20patients%20during%201990%E2%80%932016&rft.jtitle=Acta%20neurologica%20Belgica&rft.au=Ghiasian,%20Masoud&rft.date=2021-02-01&rft.volume=121&rft.issue=1&rft.spage=199&rft.epage=204&rft.pages=199-204&rft.issn=0300-9009&rft.eissn=2240-2993&rft_id=info:doi/10.1007/s13760-020-01528-7&rft_dat=%3Cproquest_cross%3E2460081032%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2460081032&rft_id=info:pmid/33180313&rfr_iscdi=true |