Sequence variants in the renin–angiotensin system genes are associated with isolated multicystic dysplastic kidney in children

Background Multicystic dysplastic kidney (MCDK) is a common form of congenital cystic kidney disease in children. The etiology of MCDK remains unclear. Given an important role of the renin–angiotensin system in normal kidney development, we explored whether MCDK in children is associated with varian...

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Veröffentlicht in:	Pediatric research 2021-07, Vol.90 (1), p.205-211
Hauptverfasser:	Song, Renfang, Yosypiv, Ihor V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensinogen - genetics Case-Control Studies Child Clinical Research Article Female Genes Genetic Predisposition to Disease Humans Male Medicine Medicine & Public Health Multicystic Dysplastic Kidney - genetics Pediatric Surgery Pediatrics Peptidyl-Dipeptidase A - genetics Receptor, Angiotensin, Type 1 - genetics Renin - genetics Renin-Angiotensin System - genetics
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