Development of a Red-Light-Controllable Nitric Oxide Releaser to Control Smooth Muscle Relaxation in Vivo

We designed and synthesized a novel Si-rhodamine derivative, NORD-1, as a red-light-controllable nitric oxide (NO) releaser, on the basis of photoredox parameter analysis. Red-light-responsive NO release from NORD-1 was confirmed by ESR spin trapping and quantified with an NO electrode and by means...

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Veröffentlicht in:ACS chemical biology 2020-11, Vol.15 (11), p.2958-2965
Hauptverfasser: Ieda, Naoya, Hotta, Yuji, Yamauchi, Ayaka, Nishikawa, Atsushi, Sasamori, Takahiro, Saitoh, Daisuke, Kawaguchi, Mitsuyasu, Kimura, Kazunori, Nakagawa, Hidehiko
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Sprache:eng
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