A ratiometric fluorescent probe based on AIEgen for detecting HClO in living cells

A ratiometric fluorescent probe based on AIEgen for detecting HClO in living cells

A new ratiometric fluorescent probe, namely TPE-RNS, has been developed for detecting intracellular HClO/ClO − in living cells and discriminating cancer cells from normal cells. Based on the ratiometric fluorescence properties conferred by the AIE and DTBET effects, this probe has excellent sensitiv...

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2020-12, Vol.56 (93), p.14613-14616
Hauptverfasser: Zhang, Weijie, Wang, He, Li, Feng, Chen, Yuncong, Kwok, Ryan T. K, Huang, Yuhua, Zhang, Jianglei, Hou, Jianquan, Tang, Ben Zhong
Format: Artikel
Sprache:eng
Schlagworte:
Cells (biology)
Fluorescent indicators
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Zusammenfassung:A new ratiometric fluorescent probe, namely TPE-RNS, has been developed for detecting intracellular HClO/ClO − in living cells and discriminating cancer cells from normal cells. Based on the ratiometric fluorescence properties conferred by the AIE and DTBET effects, this probe has excellent sensitivity and specificity for the HCIO response. A high performance ratiometric fluorescent probe, namely TPE-RNS, has been developed for detecting exogenous and endogenous HClO/ClO − in living cells and discriminating cancer cells from normal cells.
ISSN:1359-7345
1364-548X
DOI:10.1039/d0cc06582j