Novel predictive risk factor for Erectile Dysfunction: Serum folic acid
The purpose of this study was to compare the serum Folic Acid (FA) levels in patients with Erectile Dysfunction (ED) and healthy controls and whether levels vary with its severity. The study was carried out on 77 sexually active individuals, out of which 41 complained of ED and 36 were apparently no...
Gespeichert in:
| Veröffentlicht in: | Andrologia 2021-02, Vol.53 (1), p.e13890-n/a |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | n/a |
|---|---|
| container_issue | 1 |
| container_start_page | e13890 |
| container_title | Andrologia |
| container_volume | 53 |
| creator | Gupta, Abhimanyu Priyadarshi, Shivam Vyas, Nachiket Sharma, Govind Swain, Prafulla Kumar |
| description | The purpose of this study was to compare the serum Folic Acid (FA) levels in patients with Erectile Dysfunction (ED) and healthy controls and whether levels vary with its severity. The study was carried out on 77 sexually active individuals, out of which 41 complained of ED and 36 were apparently normal. Patients were excluded if they had any diseases known to cause ED. The severity was further categorised based on IIEF‐5 scores. Blood serum levels of testosterone, lipid profile, random blood sugar, liver function test, renal function test and FA levels were obtained in each patient. Independent‐samples t test of significance was used when comparing between two means. Pearson's correlation coefficient (r) test was used for correlating data. All clinical and biochemical parameters except FA were comparable in both the groups. FA levels were significantly decreased in ED group (5.29 vs. 10.8; p value = .004). Smoking habits were comparable between the groups, and FA levels did not vary among smokers and nonsmokers (p value = .46). Serum FA levels significantly declined with increasing severity of ED (8.28 vs. 5.56 vs. 4.37 vs. 3.5; p value |
| doi_str_mv | 10.1111/and.13890 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2457662998</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2479995753</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3880-301fb67ec6a92771ef669fe7bb84985d586a8dc8307585d44144f00df36803fe3</originalsourceid><addsrcrecordid>eNp1kE9LwzAYh4Mobswd_AJS8KKHbknz39vY5hTGPKjnkKYJdHbtTNbJvr3RTg-CL4Tk5X34kfcB4BLBEYo11nUxQlhIeAL6iGCZwoxnp6APMcQpoUz2wDCENYxFKOeEnIMexoggSWEfLFbN3lbJ1tuiNLtybxNfhrfEabNrfOLimXsbB5VNZofg2jq-m_oueba-3cR5VZpEm7K4AGdOV8EOj_cAvN7PX6YP6fJp8TidLFODhYAphsjljFvDtMw4R9YxJp3leS6IFLSggmlRGIEhp7ElBBHiICwcZgJiZ_EA3HS5W9-8tzbs1KYMxlaVrm3TBpXFHRnLpBQRvf6DrpvW1_F3keJSSsopjtRtRxnfhOCtU1tfbrQ_KATVl2AVBatvwZG9Oia2-cYWv-SPzgiMO-AjCjv8n6Qmq1kX-Qlf6YIg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2479995753</pqid></control><display><type>article</type><title>Novel predictive risk factor for Erectile Dysfunction: Serum folic acid</title><source>Wiley Online Library All Journals</source><creator>Gupta, Abhimanyu ; Priyadarshi, Shivam ; Vyas, Nachiket ; Sharma, Govind ; Swain, Prafulla Kumar</creator><creatorcontrib>Gupta, Abhimanyu ; Priyadarshi, Shivam ; Vyas, Nachiket ; Sharma, Govind ; Swain, Prafulla Kumar</creatorcontrib><description>The purpose of this study was to compare the serum Folic Acid (FA) levels in patients with Erectile Dysfunction (ED) and healthy controls and whether levels vary with its severity. The study was carried out on 77 sexually active individuals, out of which 41 complained of ED and 36 were apparently normal. Patients were excluded if they had any diseases known to cause ED. The severity was further categorised based on IIEF‐5 scores. Blood serum levels of testosterone, lipid profile, random blood sugar, liver function test, renal function test and FA levels were obtained in each patient. Independent‐samples t test of significance was used when comparing between two means. Pearson's correlation coefficient (r) test was used for correlating data. All clinical and biochemical parameters except FA were comparable in both the groups. FA levels were significantly decreased in ED group (5.29 vs. 10.8; p value = .004). Smoking habits were comparable between the groups, and FA levels did not vary among smokers and nonsmokers (p value = .46). Serum FA levels significantly declined with increasing severity of ED (8.28 vs. 5.56 vs. 4.37 vs. 3.5; p value < .001). Thus, decreased FA might possibly be one of the novel risk factors for ED.</description><identifier>ISSN: 0303-4569</identifier><identifier>EISSN: 1439-0272</identifier><identifier>DOI: 10.1111/and.13890</identifier><identifier>PMID: 33141950</identifier><language>eng</language><publisher>Germany: Wiley Subscription Services, Inc</publisher><subject>endothelial dysfunction ; Erectile dysfunction ; Folic acid ; folic acid deficiency ; Indian population ; Renal function ; Risk factors ; Serum levels ; Testosterone</subject><ispartof>Andrologia, 2021-02, Vol.53 (1), p.e13890-n/a</ispartof><rights>2020 Wiley‐VCH GmbH</rights><rights>2020 Wiley-VCH GmbH.</rights><rights>Copyright © 2021 Blackwell Verlag GmbH</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3880-301fb67ec6a92771ef669fe7bb84985d586a8dc8307585d44144f00df36803fe3</citedby><cites>FETCH-LOGICAL-c3880-301fb67ec6a92771ef669fe7bb84985d586a8dc8307585d44144f00df36803fe3</cites><orcidid>0000-0002-1489-3992</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fand.13890$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fand.13890$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33141950$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gupta, Abhimanyu</creatorcontrib><creatorcontrib>Priyadarshi, Shivam</creatorcontrib><creatorcontrib>Vyas, Nachiket</creatorcontrib><creatorcontrib>Sharma, Govind</creatorcontrib><creatorcontrib>Swain, Prafulla Kumar</creatorcontrib><title>Novel predictive risk factor for Erectile Dysfunction: Serum folic acid</title><title>Andrologia</title><addtitle>Andrologia</addtitle><description>The purpose of this study was to compare the serum Folic Acid (FA) levels in patients with Erectile Dysfunction (ED) and healthy controls and whether levels vary with its severity. The study was carried out on 77 sexually active individuals, out of which 41 complained of ED and 36 were apparently normal. Patients were excluded if they had any diseases known to cause ED. The severity was further categorised based on IIEF‐5 scores. Blood serum levels of testosterone, lipid profile, random blood sugar, liver function test, renal function test and FA levels were obtained in each patient. Independent‐samples t test of significance was used when comparing between two means. Pearson's correlation coefficient (r) test was used for correlating data. All clinical and biochemical parameters except FA were comparable in both the groups. FA levels were significantly decreased in ED group (5.29 vs. 10.8; p value = .004). Smoking habits were comparable between the groups, and FA levels did not vary among smokers and nonsmokers (p value = .46). Serum FA levels significantly declined with increasing severity of ED (8.28 vs. 5.56 vs. 4.37 vs. 3.5; p value < .001). Thus, decreased FA might possibly be one of the novel risk factors for ED.</description><subject>endothelial dysfunction</subject><subject>Erectile dysfunction</subject><subject>Folic acid</subject><subject>folic acid deficiency</subject><subject>Indian population</subject><subject>Renal function</subject><subject>Risk factors</subject><subject>Serum levels</subject><subject>Testosterone</subject><issn>0303-4569</issn><issn>1439-0272</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp1kE9LwzAYh4Mobswd_AJS8KKHbknz39vY5hTGPKjnkKYJdHbtTNbJvr3RTg-CL4Tk5X34kfcB4BLBEYo11nUxQlhIeAL6iGCZwoxnp6APMcQpoUz2wDCENYxFKOeEnIMexoggSWEfLFbN3lbJ1tuiNLtybxNfhrfEabNrfOLimXsbB5VNZofg2jq-m_oueba-3cR5VZpEm7K4AGdOV8EOj_cAvN7PX6YP6fJp8TidLFODhYAphsjljFvDtMw4R9YxJp3leS6IFLSggmlRGIEhp7ElBBHiICwcZgJiZ_EA3HS5W9-8tzbs1KYMxlaVrm3TBpXFHRnLpBQRvf6DrpvW1_F3keJSSsopjtRtRxnfhOCtU1tfbrQ_KATVl2AVBatvwZG9Oia2-cYWv-SPzgiMO-AjCjv8n6Qmq1kX-Qlf6YIg</recordid><startdate>202102</startdate><enddate>202102</enddate><creator>Gupta, Abhimanyu</creator><creator>Priyadarshi, Shivam</creator><creator>Vyas, Nachiket</creator><creator>Sharma, Govind</creator><creator>Swain, Prafulla Kumar</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TM</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-1489-3992</orcidid></search><sort><creationdate>202102</creationdate><title>Novel predictive risk factor for Erectile Dysfunction: Serum folic acid</title><author>Gupta, Abhimanyu ; Priyadarshi, Shivam ; Vyas, Nachiket ; Sharma, Govind ; Swain, Prafulla Kumar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3880-301fb67ec6a92771ef669fe7bb84985d586a8dc8307585d44144f00df36803fe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>endothelial dysfunction</topic><topic>Erectile dysfunction</topic><topic>Folic acid</topic><topic>folic acid deficiency</topic><topic>Indian population</topic><topic>Renal function</topic><topic>Risk factors</topic><topic>Serum levels</topic><topic>Testosterone</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gupta, Abhimanyu</creatorcontrib><creatorcontrib>Priyadarshi, Shivam</creatorcontrib><creatorcontrib>Vyas, Nachiket</creatorcontrib><creatorcontrib>Sharma, Govind</creatorcontrib><creatorcontrib>Swain, Prafulla Kumar</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Nucleic Acids Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Andrologia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gupta, Abhimanyu</au><au>Priyadarshi, Shivam</au><au>Vyas, Nachiket</au><au>Sharma, Govind</au><au>Swain, Prafulla Kumar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Novel predictive risk factor for Erectile Dysfunction: Serum folic acid</atitle><jtitle>Andrologia</jtitle><addtitle>Andrologia</addtitle><date>2021-02</date><risdate>2021</risdate><volume>53</volume><issue>1</issue><spage>e13890</spage><epage>n/a</epage><pages>e13890-n/a</pages><issn>0303-4569</issn><eissn>1439-0272</eissn><abstract>The purpose of this study was to compare the serum Folic Acid (FA) levels in patients with Erectile Dysfunction (ED) and healthy controls and whether levels vary with its severity. The study was carried out on 77 sexually active individuals, out of which 41 complained of ED and 36 were apparently normal. Patients were excluded if they had any diseases known to cause ED. The severity was further categorised based on IIEF‐5 scores. Blood serum levels of testosterone, lipid profile, random blood sugar, liver function test, renal function test and FA levels were obtained in each patient. Independent‐samples t test of significance was used when comparing between two means. Pearson's correlation coefficient (r) test was used for correlating data. All clinical and biochemical parameters except FA were comparable in both the groups. FA levels were significantly decreased in ED group (5.29 vs. 10.8; p value = .004). Smoking habits were comparable between the groups, and FA levels did not vary among smokers and nonsmokers (p value = .46). Serum FA levels significantly declined with increasing severity of ED (8.28 vs. 5.56 vs. 4.37 vs. 3.5; p value < .001). Thus, decreased FA might possibly be one of the novel risk factors for ED.</abstract><cop>Germany</cop><pub>Wiley Subscription Services, Inc</pub><pmid>33141950</pmid><doi>10.1111/and.13890</doi><tpages>0</tpages><orcidid>https://orcid.org/0000-0002-1489-3992</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0303-4569 |
| ispartof | Andrologia, 2021-02, Vol.53 (1), p.e13890-n/a |
| issn | 0303-4569 1439-0272 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2457662998 |
| source | Wiley Online Library All Journals |
| subjects | endothelial dysfunction Erectile dysfunction Folic acid folic acid deficiency Indian population Renal function Risk factors Serum levels Testosterone |
| title | Novel predictive risk factor for Erectile Dysfunction: Serum folic acid |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T17%3A23%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Novel%20predictive%20risk%20factor%20for%20Erectile%20Dysfunction:%20Serum%20folic%20acid&rft.jtitle=Andrologia&rft.au=Gupta,%20Abhimanyu&rft.date=2021-02&rft.volume=53&rft.issue=1&rft.spage=e13890&rft.epage=n/a&rft.pages=e13890-n/a&rft.issn=0303-4569&rft.eissn=1439-0272&rft_id=info:doi/10.1111/and.13890&rft_dat=%3Cproquest_cross%3E2479995753%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2479995753&rft_id=info:pmid/33141950&rfr_iscdi=true |