TMPRSS2‐ERG fusion impacts anterior tumor location in men with prostate cancer

Background In prostate cancer (PCa), lack of androgen receptor (AR) regulated TMPRSS2‐ETS‐related gene (ERG) gene fusion (ERGnegative) status has been associated with African American race; however, the implications of ERG status for the location of dominant tumors within the prostate remains unders...

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Veröffentlicht in:	The Prostate 2021-02, Vol.81 (2), p.109-117
Hauptverfasser:	Yamoah, Kosj, Lal, Priti, Awasthi, Shivanshu, Naghavi, Arash O., Rounbehler, Robert J., Gerke, Travis, Berglund, Anders E., Pow‐Sang, Julio M., Schaeffer, Edward M., Dhillon, Jasreman, Park, Jong Y., Rebbeck, Timothy R.
Format:	Artikel
Sprache:	eng
Schlagworte:	African American African Americans African Americans - genetics Androgen receptors AR signaling Cohort Studies Gene expression Gene fusion Genes Genomic analysis Humans Immunohistochemistry Male Middle Aged Myc protein Oncogene Proteins, Fusion - genetics Prostate - pathology Prostate cancer Prostatic Neoplasms - chemistry Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology RNA, Messenger TMPRSS2‐ERG Transcriptional Regulator ERG - analysis Transcriptional Regulator ERG - genetics tumor location Tumors
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