Molecular alterations in gastric cancer and the surrounding intestinal metaplastic mucosa: an analysis of isolated glands

Background Intestinal metaplasias (IMs) are generally regarded as pre-neoplastic gastric lesions. However, molecular alterations including genetic and epigenetic changes occurring in individual IM glands are not well defined. Aims We sought to identify DNA methylation status, microsatellite instabil...

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Veröffentlicht in:	Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2021-03, Vol.24 (2), p.382-391
Hauptverfasser:	Sugimoto, Ryo, Habano, Wataru, Yanagawa, Naoki, Akasaka, Risaburo, Toya, Yosuke, Sasaki, Akira, Matsumoto, Takayuki, Sugai, Tamotsu
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Aged Aged, 80 and over Allelic Imbalance - genetics Atrophy C gene Cancer Cancer Research Deoxyribonucleic acid DNA DNA methylation DNA Methylation - genetics Epigenesis, Genetic - genetics Epigenetics Female Gastric cancer Gastroenterology Glands Humans Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Intestine Male Medicine Medicine & Public Health Metaplasia - genetics Microsatellite Instability Middle Aged MLH1 protein Mucosa Oncology Original Article Stomach Neoplasms - genetics Surgical Oncology
Online-Zugang:	Volltext
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