DIM mitigates the development of experimental autoimmune encephalomyelitis by maintaining the stability and suppressive function of regulatory T cells

•Tregs proliferated but failed to prevent the autoimmune responses in EAE model.•DIM maintained the stability and suppressive function of Tregs in EAE model.•DIM alleviated the severity of EAE model not by facilitating Treg differentiation.•The influence of DIM on the activities of Tregs was in an A...

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Veröffentlicht in:Cellular immunology 2020-12, Vol.358, p.104238-104238, Article 104238
Hauptverfasser: Yang, Sujuan, Tan, Lixi, Chen, Yingying, Liu, Aiqun, Hong, Mingfan, Peng, Zhongxing
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Sprache:eng
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