Effects of salvianolate lyophilized injection combined with Xueshuantong injection in regulation of BBB function in a co-culture model of endothelial cells and pericytes

[Display omitted] •SLI, XST, Sal B, NR1 antagonized OGD/R-induced dysfunction of BBB in a co-culture model.•SLI combined with XST has better effect on basement membrane than single drug in the co-culture model.•XST, Sal B and NR1stabled BBB function via Ang/Tie2 signaling pathways. The combined use...

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Veröffentlicht in:	Brain research 2021-01, Vol.1751, p.147185-147185, Article 147185
Hauptverfasser:	Yuan, Qing, Wang, Jin-xin, Li, Rui-lin, Jia, Zhuang-zhuang, Wang, Shao-xia, Guo, Hong, Chai, Li-juan, Hu, Li-min
Format:	Artikel
Sprache:	eng
Schlagworte:	Ang-1 Ang-2 Basement membrane Blood–brain barrier Stroke Tie-2
Online-Zugang:	Volltext
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