The value of the platelet count and platelet indices in differentiation of COVID‐19 and influenza pneumonia
It is difficult to distinguish coronavirus disease‐2019 (COVID‐19) from other viral respiratory tract infections owing to the similarities in clinical and radiological findings. This study aims to determine the clinical importance of platelet count and platelet indices in the differentiation of COVI...
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| Veröffentlicht in: | Journal of medical virology 2021-04, Vol.93 (4), p.2221-2226 |
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| description | It is difficult to distinguish coronavirus disease‐2019 (COVID‐19) from other viral respiratory tract infections owing to the similarities in clinical and radiological findings. This study aims to determine the clinical importance of platelet count and platelet indices in the differentiation of COVID‐19 from influenza and the value of these parameters in the differential diagnosis of COVID‐19. The medical records of the patients and the electronic patient monitoring system were retrospectively analyzed. Demographic characteristics, admission symptoms, laboratory findings, radiological involvement, comorbidities, and mortality of the patients were recorded. Forty‐three patients diagnosed with influenza and 54 diagnosed with COVID‐19 were included in the study. The average age of the COVID‐19 patients was lower than that of the influenza patients (influenza: 60.5 years, COVID‐19: 52.4 years; pp = 0.024),.024), and the male gender was predominant in the COVID‐19 group (influenza: 42%, COVID‐19: 56%). According to laboratory findings, the mean platelet volume (MPV) and MPV/platelet ratio were statistically significantly lower, whereas the eosinophil count and platelet distribution width levels were significantly higher (p |
| doi_str_mv | 10.1002/jmv.26645 |
| format | Article |
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This study aims to determine the clinical importance of platelet count and platelet indices in the differentiation of COVID‐19 from influenza and the value of these parameters in the differential diagnosis of COVID‐19. The medical records of the patients and the electronic patient monitoring system were retrospectively analyzed. Demographic characteristics, admission symptoms, laboratory findings, radiological involvement, comorbidities, and mortality of the patients were recorded. Forty‐three patients diagnosed with influenza and 54 diagnosed with COVID‐19 were included in the study. The average age of the COVID‐19 patients was lower than that of the influenza patients (influenza: 60.5 years, COVID‐19: 52.4 years; pp = 0.024),.024), and the male gender was predominant in the COVID‐19 group (influenza: 42%, COVID‐19: 56%). According to laboratory findings, the mean platelet volume (MPV) and MPV/platelet ratio were statistically significantly lower, whereas the eosinophil count and platelet distribution width levels were significantly higher (p < 0.05) in the COVID‐19 group. It was found that the most common symptom in both groups was dyspnea and that the symptom was more prevalent among influenza patients. In the diagnosis of COVID‐19, the platelet count and platelet indices are easily accessible, inexpensive, and important parameters in terms of differential diagnosis and can help in the differentiation of COVID‐19 from influenza during seasonal outbreaks of the latter.</description><identifier>ISSN: 0146-6615</identifier><identifier>EISSN: 1096-9071</identifier><identifier>DOI: 10.1002/jmv.26645</identifier><identifier>PMID: 33135801</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Adult ; Aged ; Blood Platelets - pathology ; Coronaviruses ; COVID-19 ; COVID-19 - blood ; COVID-19 - virology ; Diagnosis ; Differential diagnosis ; Differentiation ; disease control ; Dyspnea ; Female ; Humans ; immune responses ; immunopathology ; Influenza ; influenza virus ; Influenza, Human - blood ; Laboratories ; Leukocytes (eosinophilic) ; Male ; Medical records ; Middle Aged ; Parameters ; Patients ; Platelet Count ; Platelets ; Pneumonia, Viral - blood ; Pneumonia, Viral - virology ; Public health ; Respiration ; Respiratory tract ; Respiratory tract diseases ; Retrospective Studies ; SARS coronavirus ; SARS-CoV-2 - isolation & purification ; Signs and symptoms ; Viral diseases ; Virology</subject><ispartof>Journal of medical virology, 2021-04, Vol.93 (4), p.2221-2226</ispartof><rights>2020 Wiley Periodicals LLC</rights><rights>2020 Wiley Periodicals LLC.</rights><rights>2021 Wiley Periodicals LLC</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3885-294b94a714c0845f45970cb199c4b74b171fc1002914192fc6ade5be1b8f311f3</citedby><cites>FETCH-LOGICAL-c3885-294b94a714c0845f45970cb199c4b74b171fc1002914192fc6ade5be1b8f311f3</cites><orcidid>0000-0002-4672-6179 ; 0000-0003-1836-6193 ; 0000-0002-9768-1425 ; 0000-0003-2690-4932 ; 0000-0001-5396-5402</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjmv.26645$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjmv.26645$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33135801$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ozcelik, Neslihan</creatorcontrib><creatorcontrib>Ozyurt, Songul</creatorcontrib><creatorcontrib>Yilmaz Kara, Bilge</creatorcontrib><creatorcontrib>Gumus, Aziz</creatorcontrib><creatorcontrib>Sahin, Unal</creatorcontrib><title>The value of the platelet count and platelet indices in differentiation of COVID‐19 and influenza pneumonia</title><title>Journal of medical virology</title><addtitle>J Med Virol</addtitle><description>It is difficult to distinguish coronavirus disease‐2019 (COVID‐19) from other viral respiratory tract infections owing to the similarities in clinical and radiological findings. This study aims to determine the clinical importance of platelet count and platelet indices in the differentiation of COVID‐19 from influenza and the value of these parameters in the differential diagnosis of COVID‐19. The medical records of the patients and the electronic patient monitoring system were retrospectively analyzed. Demographic characteristics, admission symptoms, laboratory findings, radiological involvement, comorbidities, and mortality of the patients were recorded. Forty‐three patients diagnosed with influenza and 54 diagnosed with COVID‐19 were included in the study. The average age of the COVID‐19 patients was lower than that of the influenza patients (influenza: 60.5 years, COVID‐19: 52.4 years; pp = 0.024),.024), and the male gender was predominant in the COVID‐19 group (influenza: 42%, COVID‐19: 56%). According to laboratory findings, the mean platelet volume (MPV) and MPV/platelet ratio were statistically significantly lower, whereas the eosinophil count and platelet distribution width levels were significantly higher (p < 0.05) in the COVID‐19 group. It was found that the most common symptom in both groups was dyspnea and that the symptom was more prevalent among influenza patients. In the diagnosis of COVID‐19, the platelet count and platelet indices are easily accessible, inexpensive, and important parameters in terms of differential diagnosis and can help in the differentiation of COVID‐19 from influenza during seasonal outbreaks of the latter.</description><subject>Adult</subject><subject>Aged</subject><subject>Blood Platelets - pathology</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>COVID-19 - blood</subject><subject>COVID-19 - virology</subject><subject>Diagnosis</subject><subject>Differential diagnosis</subject><subject>Differentiation</subject><subject>disease control</subject><subject>Dyspnea</subject><subject>Female</subject><subject>Humans</subject><subject>immune responses</subject><subject>immunopathology</subject><subject>Influenza</subject><subject>influenza virus</subject><subject>Influenza, Human - blood</subject><subject>Laboratories</subject><subject>Leukocytes (eosinophilic)</subject><subject>Male</subject><subject>Medical records</subject><subject>Middle Aged</subject><subject>Parameters</subject><subject>Patients</subject><subject>Platelet Count</subject><subject>Platelets</subject><subject>Pneumonia, Viral - blood</subject><subject>Pneumonia, Viral - virology</subject><subject>Public health</subject><subject>Respiration</subject><subject>Respiratory tract</subject><subject>Respiratory tract diseases</subject><subject>Retrospective Studies</subject><subject>SARS coronavirus</subject><subject>SARS-CoV-2 - isolation & purification</subject><subject>Signs and symptoms</subject><subject>Viral diseases</subject><subject>Virology</subject><issn>0146-6615</issn><issn>1096-9071</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kU1O3DAUxy3UCgbaBRdAkbqhiwx-8UfiZTW0ZdAgNnS2keM8C48SZxonILriCByBs_QonAQPQ1kgdfWkp9__p_dByCHQKVCanazam2kmJRc7ZAJUyVTRHD6QCQUuUylB7JH9EFaU0kJl2S7ZYwyYKChMiL-6xuRGNyMmnU2Ga_z7uG70gA0OielGPyTa18lby_naGQyxJrWzFnv0g9OD6_wmPrtczk-f7h9AvaSct9Hr_-hk7XFsO-_0J_LR6ibg59d6QH79-H41O0sXlz_ns2-L1LCiEGmmeKW4zoEbWnBhuVA5NRUoZXiV8wpysGazugIOKrNG6hpFhVAVlgFYdkCOt9513_0eMQxl64LBptEeuzGUGReykJQyEdEv79BVN_Y-ThcpRYHFK7JIfd1Spu9C6NGW6961ur8rgZabScr4hPLlCZE9ejWOVYv1G_nv6hE42QK3rsG7_5vK84vlVvkMgiaRLA</recordid><startdate>202104</startdate><enddate>202104</enddate><creator>Ozcelik, Neslihan</creator><creator>Ozyurt, Songul</creator><creator>Yilmaz Kara, Bilge</creator><creator>Gumus, Aziz</creator><creator>Sahin, Unal</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7TK</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-4672-6179</orcidid><orcidid>https://orcid.org/0000-0003-1836-6193</orcidid><orcidid>https://orcid.org/0000-0002-9768-1425</orcidid><orcidid>https://orcid.org/0000-0003-2690-4932</orcidid><orcidid>https://orcid.org/0000-0001-5396-5402</orcidid></search><sort><creationdate>202104</creationdate><title>The value of the platelet count and platelet indices in differentiation of COVID‐19 and influenza pneumonia</title><author>Ozcelik, Neslihan ; Ozyurt, Songul ; Yilmaz Kara, Bilge ; Gumus, Aziz ; Sahin, Unal</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3885-294b94a714c0845f45970cb199c4b74b171fc1002914192fc6ade5be1b8f311f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Blood Platelets - pathology</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>COVID-19 - blood</topic><topic>COVID-19 - virology</topic><topic>Diagnosis</topic><topic>Differential diagnosis</topic><topic>Differentiation</topic><topic>disease control</topic><topic>Dyspnea</topic><topic>Female</topic><topic>Humans</topic><topic>immune responses</topic><topic>immunopathology</topic><topic>Influenza</topic><topic>influenza virus</topic><topic>Influenza, Human - blood</topic><topic>Laboratories</topic><topic>Leukocytes (eosinophilic)</topic><topic>Male</topic><topic>Medical records</topic><topic>Middle Aged</topic><topic>Parameters</topic><topic>Patients</topic><topic>Platelet Count</topic><topic>Platelets</topic><topic>Pneumonia, Viral - blood</topic><topic>Pneumonia, Viral - virology</topic><topic>Public health</topic><topic>Respiration</topic><topic>Respiratory tract</topic><topic>Respiratory tract diseases</topic><topic>Retrospective Studies</topic><topic>SARS coronavirus</topic><topic>SARS-CoV-2 - isolation & purification</topic><topic>Signs and symptoms</topic><topic>Viral diseases</topic><topic>Virology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ozcelik, Neslihan</creatorcontrib><creatorcontrib>Ozyurt, Songul</creatorcontrib><creatorcontrib>Yilmaz Kara, Bilge</creatorcontrib><creatorcontrib>Gumus, Aziz</creatorcontrib><creatorcontrib>Sahin, Unal</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of medical virology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ozcelik, Neslihan</au><au>Ozyurt, Songul</au><au>Yilmaz Kara, Bilge</au><au>Gumus, Aziz</au><au>Sahin, Unal</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The value of the platelet count and platelet indices in differentiation of COVID‐19 and influenza pneumonia</atitle><jtitle>Journal of medical virology</jtitle><addtitle>J Med Virol</addtitle><date>2021-04</date><risdate>2021</risdate><volume>93</volume><issue>4</issue><spage>2221</spage><epage>2226</epage><pages>2221-2226</pages><issn>0146-6615</issn><eissn>1096-9071</eissn><abstract>It is difficult to distinguish coronavirus disease‐2019 (COVID‐19) from other viral respiratory tract infections owing to the similarities in clinical and radiological findings. This study aims to determine the clinical importance of platelet count and platelet indices in the differentiation of COVID‐19 from influenza and the value of these parameters in the differential diagnosis of COVID‐19. The medical records of the patients and the electronic patient monitoring system were retrospectively analyzed. Demographic characteristics, admission symptoms, laboratory findings, radiological involvement, comorbidities, and mortality of the patients were recorded. Forty‐three patients diagnosed with influenza and 54 diagnosed with COVID‐19 were included in the study. The average age of the COVID‐19 patients was lower than that of the influenza patients (influenza: 60.5 years, COVID‐19: 52.4 years; pp = 0.024),.024), and the male gender was predominant in the COVID‐19 group (influenza: 42%, COVID‐19: 56%). According to laboratory findings, the mean platelet volume (MPV) and MPV/platelet ratio were statistically significantly lower, whereas the eosinophil count and platelet distribution width levels were significantly higher (p < 0.05) in the COVID‐19 group. It was found that the most common symptom in both groups was dyspnea and that the symptom was more prevalent among influenza patients. In the diagnosis of COVID‐19, the platelet count and platelet indices are easily accessible, inexpensive, and important parameters in terms of differential diagnosis and can help in the differentiation of COVID‐19 from influenza during seasonal outbreaks of the latter.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>33135801</pmid><doi>10.1002/jmv.26645</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-4672-6179</orcidid><orcidid>https://orcid.org/0000-0003-1836-6193</orcidid><orcidid>https://orcid.org/0000-0002-9768-1425</orcidid><orcidid>https://orcid.org/0000-0003-2690-4932</orcidid><orcidid>https://orcid.org/0000-0001-5396-5402</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Aged Blood Platelets - pathology Coronaviruses COVID-19 COVID-19 - blood COVID-19 - virology Diagnosis Differential diagnosis Differentiation disease control Dyspnea Female Humans immune responses immunopathology Influenza influenza virus Influenza, Human - blood Laboratories Leukocytes (eosinophilic) Male Medical records Middle Aged Parameters Patients Platelet Count Platelets Pneumonia, Viral - blood Pneumonia, Viral - virology Public health Respiration Respiratory tract Respiratory tract diseases Retrospective Studies SARS coronavirus SARS-CoV-2 - isolation & purification Signs and symptoms Viral diseases Virology |
| title | The value of the platelet count and platelet indices in differentiation of COVID‐19 and influenza pneumonia |
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