Increased Indoleamine 2, 3-Dioxygenase expression modulates Th1/Th17/Th22 and Treg pathway in humans with Helicobacter Pylori-Infected gastric mucosa

Indoleamine 2, 3- dioxygenase (IDO) plays an importantrole in immunosuppressive pathway, as inhibits responsesof T cells and promotes immune tolerance. Host responsetoHelicobacter pylori (H. pylori) is involved in the infection persistenceand it is also associatedwith different clinical outcomes. Th...

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Veröffentlicht in:	Human immunology 2021-01, Vol.82 (1), p.46-53
Hauptverfasser:	Azadegan-Dehkordi, Fateme, Shirzad, Hedayatollah, Ahmadi, Reza, Bashash, Davood, Abdollahpour-Alitappeh, Meghdad, Luzza, Francesco, Larussa, Tiziana, Nahid-Samiei, Mahboobeh, Rahimian, Ghorbanali, Shafigh, Mohammad-Hadi, Bagheri, Nader
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biopsy Female Gastric Mucosa - diagnostic imaging Gastric Mucosa - immunology Gastric Mucosa - microbiology Gastric Mucosa - pathology Gastritis Gastritis - diagnosis Gastritis - immunology Gastritis - microbiology Gastritis - pathology Gastroscopy Helicobacter Infections - diagnosis Helicobacter Infections - immunology Helicobacter Infections - microbiology Helicobacter Infections - pathology Helicobacter pylori Helicobacter pylori - immunology Helicobacter pylori - isolation & purification Humans Immune Tolerance - genetics Indoleamine 2, 3 dioxygenase Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism Interleukin-22 Interleukins - metabolism Male Middle Aged Peptic ulcer disease T-cell T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism Th1 Cells - immunology Th1 Cells - metabolism Th17 Cells - immunology Th17 Cells - metabolism Up-Regulation - immunology
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