Silencing miR-125b-5p attenuates inflammatory response and apoptosis inhibition in mycobacterium tuberculosis-infected human macrophages by targeting DNA damage-regulated autophagy modulator 2 (DRAM2)

Tuberculosis is one of the most important infectious diseases worldwide and macrophage apoptosis is the major host defense mechanism against TB. We attempted to characterize the role of miRNA (miR)-125b-5p on mycobacterium tuberculosis (Mtb) infection and macrophages behaviors in vitro. According to...

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Veröffentlicht in:	Cell cycle (Georgetown, Tex.) Tex.), 2020-11, Vol.19 (22), p.3182-3194
Hauptverfasser:	Liu, Guangming, Wan, Qiufeng, Li, Jingwen, Hu, Xinying, Gu, Xingli, Xu, Sicheng
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis DRAM2 macrophage Mir-125b-5p mycobacterium tuberculosis Research Paper
Online-Zugang:	Volltext
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