Facial nerve management in patients with malignant skull base tumors
Introduction The course of the facial nerve through the cerebellopontine angle, temporal bone, and parotid gland puts the nerve at risk in cases of malignancy. In contrast to Bell’s palsy, which presents with acute facial paralysis, malignancies cause gradual or fluctuating weakness. Methods We revi...
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Veröffentlicht in: | Journal of neuro-oncology 2020-12, Vol.150 (3), p.493-500 |
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description | Introduction
The course of the facial nerve through the cerebellopontine angle, temporal bone, and parotid gland puts the nerve at risk in cases of malignancy. In contrast to Bell’s palsy, which presents with acute facial paralysis, malignancies cause gradual or fluctuating weakness.
Methods
We review malignancies affecting the facial nerve, including those involving the temporal bone, parotid gland, and cerebellopontine angle, in addition to metastatic disease. Intraoperative management of the facial nerve and long term management of facial palsy are reviewed.
Results
Intraoperative management of the facial nerve in cases of skull base malignancy may involve extensive exposure, mobilization, or rerouting of the nerve. In cases of nerve sacrifice, primary neurorrhaphy or interposition grafting may be used. Cranial nerve substitution, gracilis free functional muscle transfer, and orthodromic temporalis tendon transfer are management options for long term facial paralysis.
Conclusion
Temporal bone, parotid gland, and cerebellopontine angle malignancies pose a tremendous risk to the facial nerve. When possible, the facial nerve is preserved. If the facial nerve is sacrificed, static and dynamic reanimation strategies are used to enhance facial function. |
doi_str_mv | 10.1007/s11060-020-03635-0 |
format | Article |
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The course of the facial nerve through the cerebellopontine angle, temporal bone, and parotid gland puts the nerve at risk in cases of malignancy. In contrast to Bell’s palsy, which presents with acute facial paralysis, malignancies cause gradual or fluctuating weakness.
Methods
We review malignancies affecting the facial nerve, including those involving the temporal bone, parotid gland, and cerebellopontine angle, in addition to metastatic disease. Intraoperative management of the facial nerve and long term management of facial palsy are reviewed.
Results
Intraoperative management of the facial nerve in cases of skull base malignancy may involve extensive exposure, mobilization, or rerouting of the nerve. In cases of nerve sacrifice, primary neurorrhaphy or interposition grafting may be used. Cranial nerve substitution, gracilis free functional muscle transfer, and orthodromic temporalis tendon transfer are management options for long term facial paralysis.
Conclusion
Temporal bone, parotid gland, and cerebellopontine angle malignancies pose a tremendous risk to the facial nerve. When possible, the facial nerve is preserved. If the facial nerve is sacrificed, static and dynamic reanimation strategies are used to enhance facial function.</description><identifier>ISSN: 0167-594X</identifier><identifier>EISSN: 1573-7373</identifier><identifier>DOI: 10.1007/s11060-020-03635-0</identifier><identifier>PMID: 33113067</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>A Multidisciplinary Approach to Skull-Base Malignancies ; Bell's palsy ; Bone cancer ; Brain cancer ; Cranial nerves ; Disease management ; Facial nerve ; Long term ; Malignancy ; Medicine ; Medicine & Public Health ; Metastases ; Neurology ; Oncology ; Paralysis ; Parotid gland ; Skull ; Temporal bone ; Topic Review ; Tumors</subject><ispartof>Journal of neuro-oncology, 2020-12, Vol.150 (3), p.493-500</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020</rights><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-a38c9026a2dc7675626679e3391ec7d7194cf6cef170d91ba243ce28280c7de13</citedby><cites>FETCH-LOGICAL-c375t-a38c9026a2dc7675626679e3391ec7d7194cf6cef170d91ba243ce28280c7de13</cites><orcidid>0000-0002-1884-0521</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11060-020-03635-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11060-020-03635-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33113067$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Christopher, Laura H.</creatorcontrib><creatorcontrib>Slattery, William H.</creatorcontrib><creatorcontrib>Smith, Erin J.</creatorcontrib><creatorcontrib>Larian, Babak</creatorcontrib><creatorcontrib>Azizzadeh, Babak</creatorcontrib><title>Facial nerve management in patients with malignant skull base tumors</title><title>Journal of neuro-oncology</title><addtitle>J Neurooncol</addtitle><addtitle>J Neurooncol</addtitle><description>Introduction
The course of the facial nerve through the cerebellopontine angle, temporal bone, and parotid gland puts the nerve at risk in cases of malignancy. In contrast to Bell’s palsy, which presents with acute facial paralysis, malignancies cause gradual or fluctuating weakness.
Methods
We review malignancies affecting the facial nerve, including those involving the temporal bone, parotid gland, and cerebellopontine angle, in addition to metastatic disease. Intraoperative management of the facial nerve and long term management of facial palsy are reviewed.
Results
Intraoperative management of the facial nerve in cases of skull base malignancy may involve extensive exposure, mobilization, or rerouting of the nerve. In cases of nerve sacrifice, primary neurorrhaphy or interposition grafting may be used. Cranial nerve substitution, gracilis free functional muscle transfer, and orthodromic temporalis tendon transfer are management options for long term facial paralysis.
Conclusion
Temporal bone, parotid gland, and cerebellopontine angle malignancies pose a tremendous risk to the facial nerve. When possible, the facial nerve is preserved. If the facial nerve is sacrificed, static and dynamic reanimation strategies are used to enhance facial function.</description><subject>A Multidisciplinary Approach to Skull-Base Malignancies</subject><subject>Bell's palsy</subject><subject>Bone cancer</subject><subject>Brain cancer</subject><subject>Cranial nerves</subject><subject>Disease management</subject><subject>Facial nerve</subject><subject>Long term</subject><subject>Malignancy</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metastases</subject><subject>Neurology</subject><subject>Oncology</subject><subject>Paralysis</subject><subject>Parotid gland</subject><subject>Skull</subject><subject>Temporal bone</subject><subject>Topic Review</subject><subject>Tumors</subject><issn>0167-594X</issn><issn>1573-7373</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp9kE1LAzEQhoMotlb_gAdZ8OJldSazm-weRa0KBS8K3pY0ndat-1GTXcV_b7RVwYOHfMD75J3wCHGIcIoA-swjgoIYZFikKI1hSwwx1RRr0rQthoBKx2mePA7EnvdLAEg04a4YECESKD0Ul2NjS1NFDbtXjmrTmAXX3HRR2UQr05Xh6qO3snsKWVUuGhMi_9xXVTQ1nqOur1vn98XO3FSeDzbnSDyMr-4vbuLJ3fXtxfkktqTTLjaU2RykMnJmtdKpkkrpnIlyZKtnGvPEzpXlOWqY5Tg1MiHLMpMZhJiRRuJk3bty7UvPvivq0luuKtNw2_tCJmmaJYA6C-jxH3TZ9q4JvwuUJilRyjRQck1Z13rveF6sXFkb914gFJ-Oi7XjIjguvhyHfSSONtX9tObZz5NvqQGgNeBD1CzY_c7-p_YDSZOFbA</recordid><startdate>20201201</startdate><enddate>20201201</enddate><creator>Christopher, Laura H.</creator><creator>Slattery, William H.</creator><creator>Smith, Erin J.</creator><creator>Larian, Babak</creator><creator>Azizzadeh, Babak</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-1884-0521</orcidid></search><sort><creationdate>20201201</creationdate><title>Facial nerve management in patients with malignant skull base tumors</title><author>Christopher, Laura H. ; Slattery, William H. ; Smith, Erin J. ; Larian, Babak ; Azizzadeh, Babak</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-a38c9026a2dc7675626679e3391ec7d7194cf6cef170d91ba243ce28280c7de13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>A Multidisciplinary Approach to Skull-Base Malignancies</topic><topic>Bell's palsy</topic><topic>Bone cancer</topic><topic>Brain cancer</topic><topic>Cranial nerves</topic><topic>Disease management</topic><topic>Facial nerve</topic><topic>Long term</topic><topic>Malignancy</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metastases</topic><topic>Neurology</topic><topic>Oncology</topic><topic>Paralysis</topic><topic>Parotid gland</topic><topic>Skull</topic><topic>Temporal bone</topic><topic>Topic Review</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Christopher, Laura H.</creatorcontrib><creatorcontrib>Slattery, William H.</creatorcontrib><creatorcontrib>Smith, Erin J.</creatorcontrib><creatorcontrib>Larian, Babak</creatorcontrib><creatorcontrib>Azizzadeh, Babak</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of neuro-oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Christopher, Laura H.</au><au>Slattery, William H.</au><au>Smith, Erin J.</au><au>Larian, Babak</au><au>Azizzadeh, Babak</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Facial nerve management in patients with malignant skull base tumors</atitle><jtitle>Journal of neuro-oncology</jtitle><stitle>J Neurooncol</stitle><addtitle>J Neurooncol</addtitle><date>2020-12-01</date><risdate>2020</risdate><volume>150</volume><issue>3</issue><spage>493</spage><epage>500</epage><pages>493-500</pages><issn>0167-594X</issn><eissn>1573-7373</eissn><abstract>Introduction
The course of the facial nerve through the cerebellopontine angle, temporal bone, and parotid gland puts the nerve at risk in cases of malignancy. In contrast to Bell’s palsy, which presents with acute facial paralysis, malignancies cause gradual or fluctuating weakness.
Methods
We review malignancies affecting the facial nerve, including those involving the temporal bone, parotid gland, and cerebellopontine angle, in addition to metastatic disease. Intraoperative management of the facial nerve and long term management of facial palsy are reviewed.
Results
Intraoperative management of the facial nerve in cases of skull base malignancy may involve extensive exposure, mobilization, or rerouting of the nerve. In cases of nerve sacrifice, primary neurorrhaphy or interposition grafting may be used. Cranial nerve substitution, gracilis free functional muscle transfer, and orthodromic temporalis tendon transfer are management options for long term facial paralysis.
Conclusion
Temporal bone, parotid gland, and cerebellopontine angle malignancies pose a tremendous risk to the facial nerve. When possible, the facial nerve is preserved. If the facial nerve is sacrificed, static and dynamic reanimation strategies are used to enhance facial function.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>33113067</pmid><doi>10.1007/s11060-020-03635-0</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-1884-0521</orcidid></addata></record> |
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subjects | A Multidisciplinary Approach to Skull-Base Malignancies Bell's palsy Bone cancer Brain cancer Cranial nerves Disease management Facial nerve Long term Malignancy Medicine Medicine & Public Health Metastases Neurology Oncology Paralysis Parotid gland Skull Temporal bone Topic Review Tumors |
title | Facial nerve management in patients with malignant skull base tumors |
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