Facial nerve management in patients with malignant skull base tumors

Introduction The course of the facial nerve through the cerebellopontine angle, temporal bone, and parotid gland puts the nerve at risk in cases of malignancy. In contrast to Bell’s palsy, which presents with acute facial paralysis, malignancies cause gradual or fluctuating weakness. Methods We revi...

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Veröffentlicht in:Journal of neuro-oncology 2020-12, Vol.150 (3), p.493-500
Hauptverfasser: Christopher, Laura H., Slattery, William H., Smith, Erin J., Larian, Babak, Azizzadeh, Babak
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container_end_page 500
container_issue 3
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container_title Journal of neuro-oncology
container_volume 150
creator Christopher, Laura H.
Slattery, William H.
Smith, Erin J.
Larian, Babak
Azizzadeh, Babak
description Introduction The course of the facial nerve through the cerebellopontine angle, temporal bone, and parotid gland puts the nerve at risk in cases of malignancy. In contrast to Bell’s palsy, which presents with acute facial paralysis, malignancies cause gradual or fluctuating weakness. Methods We review malignancies affecting the facial nerve, including those involving the temporal bone, parotid gland, and cerebellopontine angle, in addition to metastatic disease. Intraoperative management of the facial nerve and long term management of facial palsy are reviewed. Results Intraoperative management of the facial nerve in cases of skull base malignancy may involve extensive exposure, mobilization, or rerouting of the nerve. In cases of nerve sacrifice, primary neurorrhaphy or interposition grafting may be used. Cranial nerve substitution, gracilis free functional muscle transfer, and orthodromic temporalis tendon transfer are management options for long term facial paralysis. Conclusion Temporal bone, parotid gland, and cerebellopontine angle malignancies pose a tremendous risk to the facial nerve. When possible, the facial nerve is preserved. If the facial nerve is sacrificed, static and dynamic reanimation strategies are used to enhance facial function.
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In contrast to Bell’s palsy, which presents with acute facial paralysis, malignancies cause gradual or fluctuating weakness. Methods We review malignancies affecting the facial nerve, including those involving the temporal bone, parotid gland, and cerebellopontine angle, in addition to metastatic disease. Intraoperative management of the facial nerve and long term management of facial palsy are reviewed. Results Intraoperative management of the facial nerve in cases of skull base malignancy may involve extensive exposure, mobilization, or rerouting of the nerve. In cases of nerve sacrifice, primary neurorrhaphy or interposition grafting may be used. Cranial nerve substitution, gracilis free functional muscle transfer, and orthodromic temporalis tendon transfer are management options for long term facial paralysis. Conclusion Temporal bone, parotid gland, and cerebellopontine angle malignancies pose a tremendous risk to the facial nerve. When possible, the facial nerve is preserved. If the facial nerve is sacrificed, static and dynamic reanimation strategies are used to enhance facial function.</description><identifier>ISSN: 0167-594X</identifier><identifier>EISSN: 1573-7373</identifier><identifier>DOI: 10.1007/s11060-020-03635-0</identifier><identifier>PMID: 33113067</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>A Multidisciplinary Approach to Skull-Base Malignancies ; Bell's palsy ; Bone cancer ; Brain cancer ; Cranial nerves ; Disease management ; Facial nerve ; Long term ; Malignancy ; Medicine ; Medicine &amp; Public Health ; Metastases ; Neurology ; Oncology ; Paralysis ; Parotid gland ; Skull ; Temporal bone ; Topic Review ; Tumors</subject><ispartof>Journal of neuro-oncology, 2020-12, Vol.150 (3), p.493-500</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020</rights><rights>Springer Science+Business Media, LLC, part of Springer Nature 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-a38c9026a2dc7675626679e3391ec7d7194cf6cef170d91ba243ce28280c7de13</citedby><cites>FETCH-LOGICAL-c375t-a38c9026a2dc7675626679e3391ec7d7194cf6cef170d91ba243ce28280c7de13</cites><orcidid>0000-0002-1884-0521</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11060-020-03635-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11060-020-03635-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33113067$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Christopher, Laura H.</creatorcontrib><creatorcontrib>Slattery, William H.</creatorcontrib><creatorcontrib>Smith, Erin J.</creatorcontrib><creatorcontrib>Larian, Babak</creatorcontrib><creatorcontrib>Azizzadeh, Babak</creatorcontrib><title>Facial nerve management in patients with malignant skull base tumors</title><title>Journal of neuro-oncology</title><addtitle>J Neurooncol</addtitle><addtitle>J Neurooncol</addtitle><description>Introduction The course of the facial nerve through the cerebellopontine angle, temporal bone, and parotid gland puts the nerve at risk in cases of malignancy. In contrast to Bell’s palsy, which presents with acute facial paralysis, malignancies cause gradual or fluctuating weakness. Methods We review malignancies affecting the facial nerve, including those involving the temporal bone, parotid gland, and cerebellopontine angle, in addition to metastatic disease. Intraoperative management of the facial nerve and long term management of facial palsy are reviewed. Results Intraoperative management of the facial nerve in cases of skull base malignancy may involve extensive exposure, mobilization, or rerouting of the nerve. In cases of nerve sacrifice, primary neurorrhaphy or interposition grafting may be used. Cranial nerve substitution, gracilis free functional muscle transfer, and orthodromic temporalis tendon transfer are management options for long term facial paralysis. Conclusion Temporal bone, parotid gland, and cerebellopontine angle malignancies pose a tremendous risk to the facial nerve. When possible, the facial nerve is preserved. If the facial nerve is sacrificed, static and dynamic reanimation strategies are used to enhance facial function.</description><subject>A Multidisciplinary Approach to Skull-Base Malignancies</subject><subject>Bell's palsy</subject><subject>Bone cancer</subject><subject>Brain cancer</subject><subject>Cranial nerves</subject><subject>Disease management</subject><subject>Facial nerve</subject><subject>Long term</subject><subject>Malignancy</subject><subject>Medicine</subject><subject>Medicine &amp; Public Health</subject><subject>Metastases</subject><subject>Neurology</subject><subject>Oncology</subject><subject>Paralysis</subject><subject>Parotid gland</subject><subject>Skull</subject><subject>Temporal bone</subject><subject>Topic Review</subject><subject>Tumors</subject><issn>0167-594X</issn><issn>1573-7373</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp9kE1LAzEQhoMotlb_gAdZ8OJldSazm-weRa0KBS8K3pY0ndat-1GTXcV_b7RVwYOHfMD75J3wCHGIcIoA-swjgoIYZFikKI1hSwwx1RRr0rQthoBKx2mePA7EnvdLAEg04a4YECESKD0Ul2NjS1NFDbtXjmrTmAXX3HRR2UQr05Xh6qO3snsKWVUuGhMi_9xXVTQ1nqOur1vn98XO3FSeDzbnSDyMr-4vbuLJ3fXtxfkktqTTLjaU2RykMnJmtdKpkkrpnIlyZKtnGvPEzpXlOWqY5Tg1MiHLMpMZhJiRRuJk3bty7UvPvivq0luuKtNw2_tCJmmaJYA6C-jxH3TZ9q4JvwuUJilRyjRQck1Z13rveF6sXFkb914gFJ-Oi7XjIjguvhyHfSSONtX9tObZz5NvqQGgNeBD1CzY_c7-p_YDSZOFbA</recordid><startdate>20201201</startdate><enddate>20201201</enddate><creator>Christopher, Laura H.</creator><creator>Slattery, William H.</creator><creator>Smith, Erin J.</creator><creator>Larian, Babak</creator><creator>Azizzadeh, Babak</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-1884-0521</orcidid></search><sort><creationdate>20201201</creationdate><title>Facial nerve management in patients with malignant skull base tumors</title><author>Christopher, Laura H. ; 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subjects A Multidisciplinary Approach to Skull-Base Malignancies
Bell's palsy
Bone cancer
Brain cancer
Cranial nerves
Disease management
Facial nerve
Long term
Malignancy
Medicine
Medicine & Public Health
Metastases
Neurology
Oncology
Paralysis
Parotid gland
Skull
Temporal bone
Topic Review
Tumors
title Facial nerve management in patients with malignant skull base tumors
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