Metabolic Disorders After Liver Transplantation
Early after surgery, liver transplant (LT) recipients often develop weight gain due to an increase of caloric intake and fat mass (without recovery of muscle frame). This modification of body composition together with a negative metabolic impact of immunosuppressive drugs leads to a high prevalence...
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Veröffentlicht in: | Metabolic syndrome and related disorders 2021-03, Vol.19 (2), p.65-69 |
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creator | Gitto, Stefano Falcini, Margherita Marra, Fabio |
description | Early after surgery, liver transplant (LT) recipients often develop weight gain due to an increase of caloric intake and fat mass (without recovery of muscle frame). This modification of body composition together with a negative metabolic impact of immunosuppressive drugs leads to a high prevalence of all the main metabolic disorders. Indeed, as expected, transplanted patients show a higher cardiovascular risk in comparison with general population. Notably, seeing the increase of mean age of transplanted population, metabolic disorders represent the true challenge for the transplant community. Considering the lack of evidences or clear indications about prevention, early diagnosis and treatment of metabolic disorders after LT, it would be mandatory to develop targeted further studies on this matter. |
doi_str_mv | 10.1089/met.2020.0068 |
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This modification of body composition together with a negative metabolic impact of immunosuppressive drugs leads to a high prevalence of all the main metabolic disorders. Indeed, as expected, transplanted patients show a higher cardiovascular risk in comparison with general population. Notably, seeing the increase of mean age of transplanted population, metabolic disorders represent the true challenge for the transplant community. Considering the lack of evidences or clear indications about prevention, early diagnosis and treatment of metabolic disorders after LT, it would be mandatory to develop targeted further studies on this matter.</description><identifier>ISSN: 1540-4196</identifier><identifier>EISSN: 1557-8518</identifier><identifier>DOI: 10.1089/met.2020.0068</identifier><identifier>PMID: 33104408</identifier><language>eng</language><publisher>United States</publisher><ispartof>Metabolic syndrome and related disorders, 2021-03, Vol.19 (2), p.65-69</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c293t-dcd7cf2ab23c6013fab8b1ba6620ed0bc8f7194626db4eb89680e4e2d3f042db3</citedby><cites>FETCH-LOGICAL-c293t-dcd7cf2ab23c6013fab8b1ba6620ed0bc8f7194626db4eb89680e4e2d3f042db3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33104408$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gitto, Stefano</creatorcontrib><creatorcontrib>Falcini, Margherita</creatorcontrib><creatorcontrib>Marra, Fabio</creatorcontrib><creatorcontrib>MEDITRA Research Group</creatorcontrib><creatorcontrib>the MEDITRA Research Group</creatorcontrib><title>Metabolic Disorders After Liver Transplantation</title><title>Metabolic syndrome and related disorders</title><addtitle>Metab Syndr Relat Disord</addtitle><description>Early after surgery, liver transplant (LT) recipients often develop weight gain due to an increase of caloric intake and fat mass (without recovery of muscle frame). This modification of body composition together with a negative metabolic impact of immunosuppressive drugs leads to a high prevalence of all the main metabolic disorders. Indeed, as expected, transplanted patients show a higher cardiovascular risk in comparison with general population. Notably, seeing the increase of mean age of transplanted population, metabolic disorders represent the true challenge for the transplant community. 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This modification of body composition together with a negative metabolic impact of immunosuppressive drugs leads to a high prevalence of all the main metabolic disorders. Indeed, as expected, transplanted patients show a higher cardiovascular risk in comparison with general population. Notably, seeing the increase of mean age of transplanted population, metabolic disorders represent the true challenge for the transplant community. Considering the lack of evidences or clear indications about prevention, early diagnosis and treatment of metabolic disorders after LT, it would be mandatory to develop targeted further studies on this matter.</abstract><cop>United States</cop><pmid>33104408</pmid><doi>10.1089/met.2020.0068</doi><tpages>5</tpages></addata></record> |
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title | Metabolic Disorders After Liver Transplantation |
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