Deep-Kcr: accurate detection of lysine crotonylation sites using deep learning method

Abstract As a newly discovered protein posttranslational modification, histone lysine crotonylation (Kcr) involved in cellular regulation and human diseases. Various proteomics technologies have been developed to detect Kcr sites. However, experimental approaches for identifying Kcr sites are often...

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Veröffentlicht in:	Briefings in bioinformatics 2021-07, Vol.22 (4)
Hauptverfasser:	Lv, Hao, Dao, Fu-Ying, Guan, Zheng-Xing, Yang, Hui, Li, Yan-Wen, Lin, Hao
Format:	Artikel
Sprache:	eng
Schlagworte:	Artificial neural networks Bayesian analysis Computer applications Deep learning Histones Long short-term memory Lysine Neural networks Physicochemical properties Proteomics Robustness (mathematics)
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