Designing topographically textured microparticles for induction and modulation of osteogenesis in mesenchymal stem cell engineering

Mesenchymal stem cells are the focus of intense research in bone development and regeneration. The potential of microparticles as modulating moieties of osteogenic response by utilizing their architectural features is demonstrated herein. Topographically textured microparticles of varying microscale...

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Veröffentlicht in:	Biomaterials 2021-01, Vol.266, p.120450-120450, Article 120450
Hauptverfasser:	Amer, Mahetab H., Alvarez-Paino, Marta, McLaren, Jane, Pappalardo, Francesco, Trujillo, Sara, Wong, Jing Qian, Shrestha, Sumana, Abdelrazig, Salah, Stevens, Lee A., Lee, Jong Bong, Kim, Dong-Hyun, González-García, Cristina, Needham, David, Salmerón-Sánchez, Manuel, Shakesheff, Kevin M., Alexander, Morgan R., Alexander, Cameron, Rose, Felicity RAJ
Format:	Artikel
Sprache:	eng
Schlagworte:	Mesenchymal stem cells Microcarriers Osteogenic differentiation Osteoinductive Topography
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