Structural and functional alterations in untreated patients with major depressive disorder and bipolar disorder experiencing first depressive episode: A magnetic resonance imaging study combined with follow-up

•Cortical and cortico-limbic changes may be biomarkers in affective disorders.•Changes in the right cerebrum were unique to patients with bipolar disorder (BD).•Patients with BD had more cerebral lesions than major depressive disorder (MDD).•Patients with BD without hypomania or mania may differenti...

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Veröffentlicht in:Journal of affective disorders 2021-01, Vol.279, p.324-333
Hauptverfasser: Jiang, Xiaowei, Wang, Xinrui, Jia, Linna, Sun, Ting, Kang, Jiahui, Zhou, Yifang, Wei, Shengnan, Wu, Feng, Kong, Lingtao, Wang, Fei, Tang, Yanqing
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Sprache:eng
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