EWSR1 overexpression is a pro-oncogenic event in multiple myeloma

Multiple myeloma (MM) is cytogenetically, genetically and molecularly heterogenous even among subclones in one patient, therefore, it is essential to identify both frequent and patient-specific drivers of molecular abnormality. Following previous molecular investigations, we in this study investigat...

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Veröffentlicht in:	International journal of hematology 2021-03, Vol.113 (3), p.381-394
Hauptverfasser:	Nishiyama, Daichi, Chinen, Yoshiaki, Isa, Reiko, Fujibayashi, Yuto, Kuwahara-Ota, Saeko, Yamaguchi, Junko, Takimoto-Shimomura, Tomoko, Matsumura-Kimoto, Yayoi, Tsukamoto, Taku, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Taniwaki, Masafumi, Handa, Hiroshi, Kuroda, Junya
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Apoptosis Cell proliferation DNA microarrays Ewing's sarcoma Ewings sarcoma EWSR1 gene FLI-1 protein Gene expression Hematology K-Ras protein Medicine Medicine & Public Health Metabolism Monoclonal gammopathy Multiple myeloma Oncology Original Article Plasma cells Sarcoma Transcription Tumor cell lines
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