TACIMA-218: A Novel Pro-Oxidant Agent Exhibiting Selective Antitumoral Activity

We report the discovery, via a unique high-throughput screening strategy, of a novel bioactive anticancer compound: hiol lkylating ompound nducing assive poptosis (TACIMA)-218. We demonstrate that this molecule engenders apoptotic cell death in genetically diverse murine and human cancer cell lines,...

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Veröffentlicht in:	Molecular cancer therapeutics 2021-01, Vol.20 (1), p.37-49
Hauptverfasser:	Abusarah, Jamilah, Cui, Yun, El-Hachem, Nehme, El-Kadiry, Abed El-Hakim, Hammond-Martel, Ian, Wurtele, Hugo, Beaudry, Annie, Raynal, Noël J-M, Robert, Francis, Pelletier, Jerry, Jankovic, Maja, Mercier, Francois, Kamyabiazar, Samaneh, Annabi, Borhane, Rafei, Moutih
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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