Triple, Mutually Orthogonal Bioorthogonal Pairs through the Design of Electronically Activated Sulfamate-Containing Cycloalkynes

Interest in mutually exclusive pairs of bioorthogonal labeling reagents continues to drive the design of new compounds that are capable of fast and predictable reactions. The ability to easily modify S-, N-, and O-containing cyclooctynes (SNO-OCTs) enables electronic tuning of various SNO-OCTs to in...

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Veröffentlicht in:	Journal of the American Chemical Society 2020-11, Vol.142 (44), p.18826-18835
Hauptverfasser:	Hu, Yun, Roberts, Jessica M, Kilgore, Henry R, Mat Lani, Amirah S, Raines, Ronald T, Schomaker, Jennifer M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CHO Cells Cricetinae Cricetulus Cycloaddition Reaction Cycloparaffins - chemistry Fluorescent Dyes - chemistry Microscopy, Fluorescence Molecular Conformation Nitrogen - chemistry Oxygen - chemistry Sulfonic Acids - chemistry Sulfur - chemistry Thermodynamics
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