Characterization of Phosphopeptide Positional Isomers on the Transcriptional Co-activator TAZ

The transcriptional co-activator with the PDZ binding motif (TAZ) is a critical regulator of numerous cellular processes such as cell differentiation, development, proliferation, and cell growth. Aberrant expression and activity of TAZ are also featured in many human malignancies. A hallmark of TAZ...

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Veröffentlicht in:	Biochemistry (Easton) 2020-11, Vol.59 (43), p.4148-4154
Hauptverfasser:	Roberto, Justin, Sykes, Catherine E, Vacratsis, Panayiotis O
Format:	Artikel
Sprache:	eng
Schlagworte:	14-3-3 Proteins - metabolism Cell Differentiation - drug effects Cell Nucleus - drug effects Cell Nucleus - metabolism Cell Proliferation - drug effects Cytoplasm - drug effects Cytoplasm - metabolism HEK293 Cells Humans Intracellular Signaling Peptides and Proteins - chemistry Intracellular Signaling Peptides and Proteins - metabolism Phosphopeptides - chemistry Phosphopeptides - pharmacology Phosphorylation Signal Transduction - physiology Trans-Activators - metabolism Transcription Factors - chemistry
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