In silico molecular docking in DNA aptamer development

Aptamers are single-stranded DNA or RNA oligonucleotides generated by SELEX that exhibit binding affinity and specificity against a wide variety of target molecules. Compared to RNA aptamers, DNA aptamers are much more stable and therefore are widely adopted in a number of applications especially in...

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Veröffentlicht in:	Biochimie 2021-01, Vol.180, p.54-67
Hauptverfasser:	Navien, Tholasi Nadhan, Thevendran, Ramesh, Hamdani, Hazrina Yusof, Tang, Thean-Hock, Citartan, Marimuthu
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA aptamer In silico In silico maturation Molecular docking Structural modeling
Online-Zugang:	Volltext
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