Development of DHQ-based chemical biology probe to profile cellular targets for HBV

[Display omitted] Chronic hepatitis B virus (HBV) infection has been a serious public health burden worldwide. Current anti-HBV therapies could not eliminate HBV ultimately. Considering the characteristics of HBV, it is impossible to be entirely cured based on current therapies. Therefore, it is urg...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2020-12, Vol.30 (23), p.127615-127615, Article 127615
Hauptverfasser:	Zhang, Qing, Huang, Jianzhou, Chow, Hoi Yee, Wang, Jinzheng, Zhang, Yingjun, Fung, Yi Man Eva, Ren, Qingyun, Li, Xuechen
Format:	Artikel
Sprache:	eng
Schlagworte:	Activity-based proteome profiling (ABPP) Dihydroquinolizinone (DHQ) Hepatitis B virus (HBV) Photoaffinity labeling RNA stability
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